Patupilone (Epothilone B) 25mg | Purity Not Available
Selleck Chemicals
Patupilone (EPO906, Epothilone B) is a paclitaxel-like microtubule-stabilizing agent with EC0.01 of 1.8 μM. Phase 2.
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BMS-707035 5mg | Purity Not Available
Selleck Chemicals
BMS-707035 is a specific HIV-I integrase (IN) inhibitor with IC50 of 15 nM. Phase 2.
More Information Supplier PageAmonafide 10mg | Purity Not Available
Selleck Chemicals
Amonafide (NSC308847, AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage. Phase 3.
More Information Supplier PageLidocaine 50mg | Purity Not Available
Selleck Chemicals
Lidocaine (Alphacaine) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM.
More Information Supplier PageLoratadine 50mg | Purity Not Available
Selleck Chemicals
Loratadine is a histamine H1 receptor antagonist, used to treat allergies. Also acts as a selective inhibitor of B(0)AT2 with IC50 of 4 μM.
More Information Supplier PageLosartan Potassium 50mg | Purity Not Available
Selleck Chemicals
Losartan Potassium is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
More Information Supplier PageLosartan Potassium 10mM/1mL | Purity Not Available
Selleck Chemicals
Losartan Potassium is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
More Information Supplier PageMGCD-265 analog 50mg | Purity Not Available
Selleck Chemicals
MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively; also inhibits Ron and Tie2. Phase 1/2.
More Information Supplier PageMGCD-265 analog 10mM/1mL | Purity Not Available
Selleck Chemicals
MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively; also inhibits Ron and Tie2. Phase 1/2.
More Information Supplier PageRigosertib (ON-01910) 5mg | Purity Not Available
Selleck Chemicals
Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM in a cell-free assay. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induces apoptosis in various cancer cells. Phase 3.
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