AUY922 (NVP-AUY922) is highly potent and oral inhibitor of Hsp90 with IC50=21 nM in Hsp90 FP binding assay and inhibits proliferation of various human cancer cell lines in vitro, with GI50 average 9 nM.
More Information Supplier PageAUY922 (NVP-AUY922) is highly potent and oral inhibitor of Hsp90 with IC50=21 nM in Hsp90 FP binding assay and inhibits proliferation of various human cancer cell lines in vitro, with GI50 average 9 nM.
More Information Supplier PageAUY922 (NVP-AUY922) is highly potent and oral inhibitor of Hsp90 with IC50=21 nM in Hsp90 FP binding assay and inhibits proliferation of various human cancer cell lines in vitro, with GI50 average 9 nM.
More Information Supplier PageNVP-BHG712 is a selective inhibitor of EphB4 kinase that exhibits selectivity for EphB4 over more than 40 other kinases in vitro, including FGFR3.
More Information Supplier PageNVP-BHG712 is a selective inhibitor of EphB4 kinase that exhibits selectivity for EphB4 over more than 40 other kinases in vitro, including FGFR3.
More Information Supplier PageNXY-059 is the disulfonyl derivative of the neuroprotective spin trap pheny lbutynitrone or “PBN” with free radical-trapping properties. It substantially lessens the functional disability resulting from cerebral ischemia in a primate species.
More Information Supplier PageNXY-059 is the disulfonyl derivative of the neuroprotective spin trap pheny lbutynitrone or “PBN” with free radical-trapping properties. It substantially lessens the functional disability resulting from cerebral ischemia in a primate species.
More Information Supplier PageNXY-059 is the disulfonyl derivative of the neuroprotective spin trap pheny lbutynitrone or “PBN” with free radical-trapping properties. It substantially lessens the functional disability resulting from cerebral ischemia in a primate species.
More Information Supplier PageTAE684 is a inhibitor of ALK and also a potent inhibitor of LRRK2 kinase activity (IC(50) of 7.8nM against wild-type LRRK2, 6.1nM against the G2019S mutant).
More Information Supplier PageTAE684 is a inhibitor of ALK and also a potent inhibitor of LRRK2 kinase activity (IC(50) of 7.8nM against wild-type LRRK2, 6.1nM against the G2019S mutant).
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