TRAM-34 is a highly selective blocker of intermediate conductance Ca2+-activated K+ channels (KCa3.1) (Kd = 20 nM). Exhibits 200-1500-fold selectivity over KV, BKCa, KCa2, Na+, CRAC and Cl- channels. Suppresses the reactivation of lymphocytes by mitogenic stimuli.
More Information Supplier PageOctreotide is a peptide agonist for sst2, sst3 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: 290 – 1140 (sst1), 0.4 – 2.1 (sst2), 4.4 – 34.5 (sst3), > 1000 (sst4), and 5.6 – 32 (sst5).
More Information Supplier PageOctreotide is a peptide agonist for sst2, sst3 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: 290 – 1140 (sst1), 0.4 – 2.1 (sst2), 4.4 – 34.5 (sst3), > 1000 (sst4), and 5.6 – 32 (sst5).
More Information Supplier PageOctreotide is a peptide agonist for sst2, sst3 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: 290 – 1140 (sst1), 0.4 – 2.1 (sst2), 4.4 – 34.5 (sst3), > 1000 (sst4), and 5.6 – 32 (sst5).
More Information Supplier PageOctreotide is a peptide agonist for sst2, sst3 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: 290 – 1140 (sst1), 0.4 – 2.1 (sst2), 4.4 – 34.5 (sst3), > 1000 (sst4), and 5.6 – 32 (sst5).
More Information Supplier PageIbutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue.
More Information Supplier PageIbutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue.
More Information Supplier PageIbutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue.
More Information Supplier PageIbutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue.
More Information Supplier PageLDE225 is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity.
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