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PD123319 25mg  | Purity Not Available

Selleck Chemicals

PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM.

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PD123319 5mg  | Purity Not Available

Selleck Chemicals

PD 123319 is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM.

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HSP990 (NVP-HSP990) 100mg  | Purity Not Available

Selleck Chemicals

HSP990 (NVP-HSP990) is a novel, potent and selective HSP90 inhibitor for HSP90α/β with IC50 of 0.6 nM/0.8 nM. NVP-HSP990 induces cell cycle arrest and apoptosis.

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HSP990 (NVP-HSP990) 25mg  | Purity Not Available

Selleck Chemicals

HSP990 (NVP-HSP990) is a novel, potent and selective HSP90 inhibitor for HSP90α/β with IC50 of 0.6 nM/0.8 nM. NVP-HSP990 induces cell cycle arrest and apoptosis.

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VE-821 50mg  | Purity Not Available

Selleck Chemicals

VE-821(ATR inhibitor IV) is a potent and selective ATP competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM in cell-free assays, shows inhibition of H2AX phosphorylation, minimal activity against PIKKs ATM, DNA-PK, mTOR and PI3Kγ.

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T0901317 100mg  | Purity Not Available

Selleck Chemicals

T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of 20nM for LXRα and 5 μM for FXR, respectively. T0901317 is a dual inverse agonist of RORα and RORγ with Ki of 132 nM and 51 nM, respectively. T0901317 significantly suppresses cell proliferation and induces apoptosis.

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Cilengitide trifluoroacetate 10mM/1mL  | Purity Not Available

Selleck Chemicals

Cilengitide (EMD 121974, NSC 707544) is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.

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SGC 0946 50mg  | Purity Not Available

Selleck Chemicals

SGC 0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50 of 0.3 nM in a cell-free assay, is inactive against a panel of 12 PMTs and DNMT1.

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Ceritinib 5mg  | Purity Not Available

Selleck Chemicals

Ceritinib is a potent inhibitor against ALK with IC50 of 0.2 nM in cell-free assays. Ceritinib (LDK378) also inhibits IGF-1R, InsR, STK22D and FLT3 with IC50 of 8 nM, 7 nM, 23 nM and 60 nM, respectively. Phase 3.

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