SANT-1 50mg | Purity Not Available
Selleck Chemicals
SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist effects with IC50 of 20 nM.
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SANT-1 10mg | Purity Not Available
Selleck Chemicals
SANT-1 directly binds to Smoothened (Smo) receptor with Kd of 1.2 nM and inhibits Smo agonist effects with IC50 of 20 nM.
More Information Supplier PageZotarolimus (ABT-578) 25mg | Purity Not Available
Selleck Chemicals
Zotarolimus (ABT-578,A 179578) is an analogue of rapamycin, and inhibits FKBP-12 binding with IC50 of 2.8 nM.
More Information Supplier PageZotarolimus (ABT-578) 5mg | Purity Not Available
Selleck Chemicals
Zotarolimus (ABT-578,A 179578) is an analogue of rapamycin, and inhibits FKBP-12 binding with IC50 of 2.8 nM.
More Information Supplier PageGSK923295 50mg | Purity Not Available
Selleck Chemicals
GSK923295 is a first-in-class, specific allosteric inhibitor of CENP-E kinesin motor ATPase with Ki of 3.2 nM, and less potent to mutant I182 and T183. GSK923295 induces post-mitotic apoptosis. Phase 1.
More Information Supplier PagePF-3758309 50mg | Purity Not Available
Selleck Chemicals
PF-03758309 (PF-03758309) is a potent, ATP-competitive, pyrrolopyrazole inhibitor of PAK4 with Kd of 2.7 nM. PF-3758309 is antiproliferative and induces apoptosis in a HCT116 tumor model.
More Information Supplier PageKY02111 50mg | Purity Not Available
Selleck Chemicals
KY02111 promotes differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, may act downstream of APC and GSK3β.
More Information Supplier PageHSP990 (NVP-HSP990) 5mg | Purity Not Available
Selleck Chemicals
HSP990 (NVP-HSP990) is a novel, potent and selective HSP90 inhibitor for HSP90α/β with IC50 of 0.6 nM/0.8 nM. NVP-HSP990 induces cell cycle arrest and apoptosis.
More Information Supplier Page(-)-Blebbistatin 10mM/1mL | Purity Not Available
Selleck Chemicals
(-)-Blebbistatin ((S)-(-)-Blebbistatin) is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM in cell-free assays, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly.
More Information Supplier Page(-)-Blebbistatin 25mg | Purity Not Available
Selleck Chemicals
(-)-Blebbistatin ((S)-(-)-Blebbistatin) is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM in cell-free assays, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly.
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