Berzosertib (VE-822) 10mg | Purity Not Available
Selleck Chemicals
Berzosertib (VE-822, VX970, M6620) is an ATR inhibitor with IC50 of 19 nM in HT29 cells.
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AZD3463 50mg | Purity Not Available
Selleck Chemicals
AZD3463 is a novel orally bioavailable ALK inhibitor with Ki of 0.75 nM, which also inhibits IGF1R with equivalent potency. AZD3463 suppresses cell viability by inducing both cell apoptosis and autophagy.
More Information Supplier PageEncorafenib 1mg | Purity Not Available
Selleck Chemicals
Encorafenib is a highly potent RAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing B-RAF(V600E) with EC50 of 4 nM. Phase 3.
More Information Supplier PageEncorafenib 5mg | Purity Not Available
Selleck Chemicals
Encorafenib is a highly potent RAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing B-RAF(V600E) with EC50 of 4 nM. Phase 3.
More Information Supplier Page(+)-JQ1 25mg | Purity Not Available
Selleck Chemicals
(+)-JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+)-JQ1 suppresses cell proliferation via inducing autophagy. (+)-JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.
More Information Supplier PageIDO-IN-2 10mg | Purity Not Available
Selleck Chemicals
IDO-IN-2 (RG 6078, NLG-919 analogue, GDC-0919 analogue) is a a potent IDO1 inhibitor with IC50 of 38 nM.
More Information Supplier PageIDO-IN-2 50mg | Purity Not Available
Selleck Chemicals
IDO-IN-2 (RG 6078, NLG-919 analogue, GDC-0919 analogue) is a a potent IDO1 inhibitor with IC50 of 38 nM.
More Information Supplier PageZebularine (NSC 309132) 50mg | Purity Not Available
Selleck Chemicals
Zebularine (NSC 309132, 4-Deoxyuridine) is a DNA methylation inhibitor that forms a covalent complex with DNA methyltransferases, also inhibits cytidinedeaminase with Ki of 2 μM in a cell-free assay.
More Information Supplier PageAMG-517 5mg | Purity Not Available
Selleck Chemicals
AMG 517 is a potent and selective TRPV1 antagonist, and antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM， respectively.
More Information Supplier PageIPA-3 50mg | Purity Not Available
Selleck Chemicals
IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM in a cell-free assay, no inhibition to group II PAKs (PAKs 4-6).
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