Spebrutinib (AVL-292) 10mg | Purity Not Available
Selleck Chemicals
Spebrutinib (AVL-292) is a covalent, orally active, and highly selective BTK inhibitor with IC50 of
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Setanaxib (GKT137831) 100mg | Purity Not Available
Selleck Chemicals
Setanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis.
More Information Supplier PageSetanaxib (GKT137831) 25mg | Purity Not Available
Selleck Chemicals
Setanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis.
More Information Supplier PageSSR128129E 20mg | Purity Not Available
Selleck Chemicals
SSR128129E is an orally-active and allosteric FGFR1 inhibitor with IC50 of 1.9 μM, while not affecting other related RTKs.
More Information Supplier PageGSK343 25mg | Purity Not Available
Selleck Chemicals
GSK343 is a potent and selective EZH2 inhibitor with IC50 of 4 nM in a cell-free assay, showing 60 fold selectivity against EZH1, and >1000 fold selectivity against other histone methyltransferases. GSK343 induces autophagy.
More Information Supplier PageSpebrutinib (AVL-292) 50mg | Purity Not Available
Selleck Chemicals
Spebrutinib (AVL-292) is a covalent, orally active, and highly selective BTK inhibitor with IC50 of
More Information Supplier PageSKI II 25mg | Purity Not Available
Selleck Chemicals
SKI II (SphK-I2) is a highly selective and non ATP-competitive sphingosine kinase (SphK) inhibitor with IC50 of 0.5 μM, while exhibiting no inhibitory action on other kinases including PI3K, PKCα and ERK2.
More Information Supplier PageSKI II 100mg | Purity Not Available
Selleck Chemicals
SKI II (SphK-I2) is a highly selective and non ATP-competitive sphingosine kinase (SphK) inhibitor with IC50 of 0.5 μM, while exhibiting no inhibitory action on other kinases including PI3K, PKCα and ERK2.
More Information Supplier PageSiponimod (BAF312) 5mg | Purity Not Available
Selleck Chemicals
BAF312 (Siponimod) is a next-generation S1P receptor agonist, selective for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, exhibits >1000-fold selectivity over S1P2, S1P3 and S1P4 receptors. Phase 3.
More Information Supplier PageSiponimod (BAF312) 25mg | Purity Not Available
Selleck Chemicals
BAF312 (Siponimod) is a next-generation S1P receptor agonist, selective for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, exhibits >1000-fold selectivity over S1P2, S1P3 and S1P4 receptors. Phase 3.
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