UNC2250 50mg | Purity Not Available
Selleck Chemicals
UNC2250 is a potent and selective Mer inhibitor with IC50 of 1.7 nM, about 160- and 60-fold selectivity over the closely related kinases Axl/Tyro3.
More Information Supplier PageSearch Results
URMC-099 25mg | Purity Not Available
Selleck Chemicals
URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2 activity with IC50 of 11 nM. URMC-099 also inhibits ABL1 with IC50 of 6.8 nM. URMC-099 induces autophagy.
More Information Supplier PageJSH-23 25mg | Purity Not Available
Selleck Chemicals
JSH-23 is an inhibitor of NF-κB transcriptional activity with IC50 of 7.1 μM in RAW 264.7 cell line.
More Information Supplier PageEPZ004777 5mg | Purity Not Available
Selleck Chemicals
EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM in a cell-free assay and demonstrates >1,200-fold selectivity for DOT1L over all other tested PMTs. EPZ004777 induces apoptosis.
More Information Supplier PageEPZ004777 50mg | Purity Not Available
Selleck Chemicals
EPZ004777 is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM in a cell-free assay and demonstrates >1,200-fold selectivity for DOT1L over all other tested PMTs. EPZ004777 induces apoptosis.
More Information Supplier PageARQ 621 5mg | Purity Not Available
Selleck Chemicals
ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.
More Information Supplier PageARQ 621 25mg | Purity Not Available
Selleck Chemicals
ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.
More Information Supplier PageHS-173 25mg | Purity Not Available
Selleck Chemicals
PF-562271 HCl 5mg | Purity Not Available
Selleck Chemicals
PF-562271 HCl is the hydrochloride salt of PF-562271, which is a potent, ATP-competitive, reversible inhibitor of FAK with IC50 of 1.5 nM, ~10-fold less potent for Pyk2 than FAK and >100-fold selectivity against other protein kinases, except for some CDKs. Phase 1.
More Information Supplier PagePoziotinib 5mg | Purity Not Available
Selleck Chemicals
Poziotinib is an irreversible pan-HER inhibitor with IC50 of 3.2 nM, 5.3 nM and 23.5 nM for HER1, HER2, and HER4, respectively. Poziotinib also induces apoptosis and G1 cell cycle arrest. Phase 2.
More Information Supplier Page