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GNF-5837 50mg  | Purity Not Available

Selleck Chemicals

GNF-5837 is a selective, and orally bioavailable pan-TRK inhibitor for TrkA, and TrkB with IC50 of 8 nM, and 12 nM, respectively.

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Darapladib 5mg  | Purity Not Available

Selleck Chemicals

Darapladib is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.25 nM. Phase 3.

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Darapladib 25mg  | Purity Not Available

Selleck Chemicals

Darapladib is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor with IC50 of 0.25 nM. Phase 3.

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Entospletinib (GS-9973) 10mg  | Purity Not Available

Selleck Chemicals

Entospletinib (GS-9973) is an orally bioavailable, selective Syk inhibitor with IC50 of 7.7 nM in a cell-free assay and showed 13- to >1000-fold cellular selectivity for Syk over other kinases(including Jak2, ckit, Flt3, Ret, KDR) as assessed by target protein phosphorylation or functional response.

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Entospletinib (GS-9973) 50mg  | Purity Not Available

Selleck Chemicals

Entospletinib (GS-9973) is an orally bioavailable, selective Syk inhibitor with IC50 of 7.7 nM in a cell-free assay and showed 13- to >1000-fold cellular selectivity for Syk over other kinases(including Jak2, ckit, Flt3, Ret, KDR) as assessed by target protein phosphorylation or functional response.

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GNE-7915 50mg  | Purity Not Available

Selleck Chemicals

GNE-7915 is a highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) inhibitor, with IC50 and Ki of 9 nM and 1 nM, respectively.

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GNF-5 100mg  | Purity Not Available

Selleck Chemicals

GNF-5 is a selective and allosteric Bcr-Abl inhibitor with IC50 of 220 nM.

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XMD8-92 50mg  | Purity Not Available

Selleck Chemicals

XMD8-92 is a potent and selective dual inhibitor of big map kinase (BMK1, ERK5) and bromodomain-containing proteins (BRDs, BET) with Kd of 80 nM and 170 nM for ERK5 and BRD4(1), respectively.

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