Lomeguatrib 50mg | Purity Not Available
Selleck Chemicals
Lomeguatrib (PaTrin-2) is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase with IC50 of 5 nM.
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Pacritinib 5mg | Purity Not Available
Selleck Chemicals
Pacritinib is a potent and selective inhibitor of Janus Kinase 2 (JAK2) and Fms-Like Tyrosine Kinase-3 (FLT3) with IC50s of 23 and 22 nM in cell-free assays, respectively. Phase 3.
More Information Supplier PageRiviciclib hydrochloride (P276-00) 5mg | Purity Not Available
Selleck Chemicals
Riviciclib hydrochloride (P276-00) is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Riviciclib hydrochloride (P276-00) induces apoptosis. Phase 2/3.
More Information Supplier PageNutlin-3a 5mg | Purity Not Available
Selleck Chemicals
Nutlin-3a ((-)-Nutlin-3), the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM in a cell-free assay. Nutlin-3a induces autophagy and apoptosis in a p53-dependent manner.
More Information Supplier PageNutlin-3a 25mg | Purity Not Available
Selleck Chemicals
Nutlin-3a ((-)-Nutlin-3), the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM in a cell-free assay. Nutlin-3a induces autophagy and apoptosis in a p53-dependent manner.
More Information Supplier PageSabutoclax 5mg | Purity Not Available
Selleck Chemicals
Sabutoclax (BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.
More Information Supplier PageSabutoclax 50mg | Purity Not Available
Selleck Chemicals
Sabutoclax (BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.
More Information Supplier PagePluriSIn #1 (NSC 14613) 50mg | Purity Not Available
Selleck Chemicals
PluriSIn #1 is an inhibitor of the stearoyl-coA desaturase 1 (SCD1), which is able to selectively eliminate hPSCs.
More Information Supplier PagePluriSIn #1 (NSC 14613) 10mg | Purity Not Available
Selleck Chemicals
PluriSIn #1 is an inhibitor of the stearoyl-coA desaturase 1 (SCD1), which is able to selectively eliminate hPSCs.
More Information Supplier PageGANT61 50mg | Purity Not Available
Selleck Chemicals
GANT61 (NSC 136476) is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog with IC50 of 5 μM in GLI1 expressing HEK293T cell, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation. GANT61 induces apoptosis and activates protective autophagy in LX-2 cells.
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