AT13387 is a targeted inhibitor of Hsp90,inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival.
More Information Supplier PageSB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3?? with an IC50 value of 78 nM (similar potency for GSK3??) and a Ki value of 31 nM.
More Information Supplier PageSB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3?? with an IC50 value of 78 nM (similar potency for GSK3??) and a Ki value of 31 nM.
More Information Supplier PageAZ628 is a RAF inhibitor with IC50 values: ca 30 nM for BRAF V600E and wild-type CRAF and 100 nM for wild-type BRAF.
More Information Supplier PageAZ628 is a RAF inhibitor with IC50 values: ca 30 nM for BRAF V600E and wild-type CRAF and 100 nM for wild-type BRAF.
More Information Supplier PageCX-5461 is a first-in-class non-genotoxic small molecule targeted inhibitor of RNA polymerase I (Pol I) that activates the p53 pathway without causing DNA damage.
More Information Supplier PageCX-5461 is a first-in-class non-genotoxic small molecule targeted inhibitor of RNA polymerase I (Pol I) that activates the p53 pathway without causing DNA damage.
More Information Supplier PageCX-5461 is a first-in-class non-genotoxic small molecule targeted inhibitor of RNA polymerase I (Pol I) that activates the p53 pathway without causing DNA damage.
More Information Supplier PageYM201636 is a cell-permeable and selective inhibitor of PIKfyve (IC50 = 33 nM).
More Information Supplier PageYM201636 is a cell-permeable and selective inhibitor of PIKfyve (IC50 = 33 nM).
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