FMK is potent, highly specific and irreversible inhibitor of p90 ribosomal protein S6 kinase RSK1 and RSK2; Fmk binds in the CTKD ATP-binding site and inhibits RSK autophosphorylation at Ser386. Fmk induces significant apoptosis in human FGFR3-expressing, t(4;14)-positive multiple myeloma cells.
More Information Supplier PageFMK is potent, highly specific and irreversible inhibitor of p90 ribosomal protein S6 kinase RSK1 and RSK2; Fmk binds in the CTKD ATP-binding site and inhibits RSK autophosphorylation at Ser386. Fmk induces significant apoptosis in human FGFR3-expressing, t(4;14)-positive multiple myeloma cells.
More Information Supplier PageFMK is potent, highly specific and irreversible inhibitor of p90 ribosomal protein S6 kinase RSK1 and RSK2; Fmk binds in the CTKD ATP-binding site and inhibits RSK autophosphorylation at Ser386. Fmk induces significant apoptosis in human FGFR3-expressing, t(4;14)-positive multiple myeloma cells.
More Information Supplier PageGW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor
More Information Supplier PageGW 5074 is a potent, selective and cell-permeable c-Raf1 kinase inhibitor
More Information Supplier PageGW843682X is a selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC50 values are 2.2 and 9.1 nM respectively).
More Information Supplier PageGW843682X is a selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC50 values are 2.2 and 9.1 nM respectively).
More Information Supplier PageGW501516 (GW1516 or GSK-516) is a drug that acts as a PPAR?? modulator.
More Information Supplier PageGW501516 (GW1516 or GSK-516) is a drug that acts as a PPAR?? modulator.
More Information Supplier PageGW501516 (GW1516 or GSK-516) is a drug that acts as a PPAR?? modulator.
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