RKI-1447 50mg | Purity Not Available
Selleck Chemicals
RKI-1447 is a potent inhibitor of ROCK1 and ROCK2, with IC50 of 14.5 nM and 6.2 nM, respectively, has anti-invasive and antitumor activities.
More Information Supplier PageSearch Results
BIO 50mg | Purity Not Available
Selleck Chemicals
BIO (GSK-3 Inhibitor IX, 6-bromoindirubin-3-oxime, 6-Bromoindirubin-3′-oxime, MLS 2052) is a specific inhibitor of GSK-3 with IC50 of 5 nM for GSK-3α/β in a cell-free assay, shows >16-fold selectivity over CDK5, also a pan-JAK inhibitor with IC50 of 30 nM for Tyk2. BIO induces apoptosis in human melanoma cells.
More Information Supplier PageFosbretabulin (Combretastatin A4 Phosphate) Disodium 25mg | Purity Not Available
Selleck Chemicals
Fosbretabulin (Combretastatin A4 Phosphate) Disodium is the water-soluble prodrug of Combretastatin A4 (CA4), which is a microtubule-targeting agent that binds β-tubulin with Kd of 0.4 μM in a cell-free assay. Fosbretabulin Disodium inhibits the polymerization of tubulin with IC50 of 2.4 μM, and also disrupts tumor vasculature. Fosbretabulin disodium induces mitotic arrest and apoptosis in […]
More Information Supplier PageIdasanutlin (RG7388) 5mg | Purity Not Available
Selleck Chemicals
Idasanutlin (RG7388) is a potent and selective p53-MDM2 inhibitor with IC50 of 6 nM showing improved in vitro binding as well as cellular potency/selectivity.
More Information Supplier PageIdasanutlin (RG7388) 25mg | Purity Not Available
Selleck Chemicals
Idasanutlin (RG7388) is a potent and selective p53-MDM2 inhibitor with IC50 of 6 nM showing improved in vitro binding as well as cellular potency/selectivity.
More Information Supplier PageSpebrutinib (AVL-292) 10mg | Purity Not Available
Selleck Chemicals
Spebrutinib (AVL-292) is a covalent, orally active, and highly selective BTK inhibitor with IC50 of
More Information Supplier PageSetanaxib (GKT137831) 100mg | Purity Not Available
Selleck Chemicals
Setanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis.
More Information Supplier PageSetanaxib (GKT137831) 25mg | Purity Not Available
Selleck Chemicals
Setanaxib (GKT137831, GKT831) is a potent, dual NADPH oxidase NOX1/NOX4 inhibitor with Ki of 110 nM and 140 nM, respectively. Treatment with GKT137831 suppresses reactive oxygen species (ROS) production. GKT137831 partly inhibits ferroptosis.
More Information Supplier PageSSR128129E 20mg | Purity Not Available
Selleck Chemicals
SSR128129E is an orally-active and allosteric FGFR1 inhibitor with IC50 of 1.9 μM, while not affecting other related RTKs.
More Information Supplier PageGSK343 25mg | Purity Not Available
Selleck Chemicals
GSK343 is a potent and selective EZH2 inhibitor with IC50 of 4 nM in a cell-free assay, showing 60 fold selectivity against EZH1, and >1000 fold selectivity against other histone methyltransferases. GSK343 induces autophagy.
More Information Supplier Page