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ASP3026 50mg  | Purity Not Available

Selleck Chemicals

ASP3026 is a novel and selective inhibitor for ALK with IC50 of 3.5 nM. Phase 1.

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Lomeguatrib 50mg  | Purity Not Available

Selleck Chemicals

Lomeguatrib (PaTrin-2) is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase with IC50 of 5 nM.

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Pacritinib 5mg  | Purity Not Available

Selleck Chemicals

Pacritinib is a potent and selective inhibitor of Janus Kinase 2 (JAK2) and Fms-Like Tyrosine Kinase-3 (FLT3) with IC50s of 23 and 22 nM in cell-free assays, respectively. Phase 3.

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Riviciclib hydrochloride (P276-00) 5mg  | Purity Not Available

Selleck Chemicals

Riviciclib hydrochloride (P276-00) is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively. Riviciclib hydrochloride (P276-00) induces apoptosis. Phase 2/3.

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Nutlin-3a 5mg  | Purity Not Available

Selleck Chemicals

Nutlin-3a ((-)-Nutlin-3), the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM in a cell-free assay. Nutlin-3a induces autophagy and apoptosis in a p53-dependent manner.

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Nutlin-3a 25mg  | Purity Not Available

Selleck Chemicals

Nutlin-3a ((-)-Nutlin-3), the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM in a cell-free assay. Nutlin-3a induces autophagy and apoptosis in a p53-dependent manner.

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Sabutoclax 5mg  | Purity Not Available

Selleck Chemicals

Sabutoclax (BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.

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Sabutoclax 50mg  | Purity Not Available

Selleck Chemicals

Sabutoclax (BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.

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