TRV130 is an opioid drug that is under evaluation in human clinical trials for the treatment of acute severe pain. TRV130 elicits robust G protein signaling, with potency and efficacy similar to morphine, but with far less ??-arrestin 2 recruitment and receptor internalization, it displays less adverse effects than morphine.
More Information Supplier PageTRV130 is an opioid drug that is under evaluation in human clinical trials for the treatment of acute severe pain. TRV130 elicits robust G protein signaling, with potency and efficacy similar to morphine, but with far less ??-arrestin 2 recruitment and receptor internalization, it displays less adverse effects than morphine.
More Information Supplier PageValrubicin is a semisynthetic derivative of the antineoplastic anthracycline antibiotic doxorubicin.
More Information Supplier PageValrubicin is a semisynthetic derivative of the antineoplastic anthracycline antibiotic doxorubicin.
More Information Supplier PageValrubicin is a semisynthetic derivative of the antineoplastic anthracycline antibiotic doxorubicin.
More Information Supplier PageBMH-21 is a potent small molecule DNA intercalator. BMH-21 binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription.
More Information Supplier PageBMH-21 is a potent small molecule DNA intercalator. BMH-21 binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription.
More Information Supplier PagePI-3065 is a small molecule and selective inhibitor of p110??kinase with an Ki value of 1.5nM and IC50 value of 5nM
More Information Supplier PagePI-3065 is a small molecule and selective inhibitor of p110??kinase with an Ki value of 1.5nM and IC50 value of 5nM
More Information Supplier PagePI-3065 is a small molecule and selective inhibitor of p110??kinase with an Ki value of 1.5nM and IC50 value of 5nM
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