AR-A 014418 is a selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC50 values are > 100 ??M) and over 26 other kinases. Inhibits ??-amyloid-mediated neurodegeneration in hippocampal slices.
More Information Supplier PageAR-A 014418 is a selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC50 values are > 100 ??M) and over 26 other kinases. Inhibits ??-amyloid-mediated neurodegeneration in hippocampal slices.
More Information Supplier PageAR-A 014418 is a selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104 nM). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC50 values are > 100 ??M) and over 26 other kinases. Inhibits ??-amyloid-mediated neurodegeneration in hippocampal slices.
More Information Supplier PageMDL-29951 is a novel glycine antagonist of NMDA receptor activation (Ki=0.14 mM, [3H]glycine binding) in vitro and in vivo.
More Information Supplier PageMDL-29951 is a novel glycine antagonist of NMDA receptor activation (Ki=0.14 mM, [3H]glycine binding) in vitro and in vivo.
More Information Supplier PageJW 55 is an inhibitor of the PARP domain of tankyrase 1 and 2 (TNKS1/2).
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