Non-peptidic anti-diabetic agent. Receptor-selective glucagon antagonist. Free radical species (·OH, R·) and singlet oxygen (1O2) scavenger. Mycotoxin. Cytotoxic. Antioxidant. Inhibitor of botulinum neurotoxin serotype A (BoNTA). Anti-MRSA compound. Antibiotic.
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Cell/membrane permeable, non-toxic, pH-sensitive fluorescent dye (blue-green range) for live imaging of pH alteration in acidic organelles, lysosomes, autophagolysosomes, vesicles, cells, tissue and even small, transparent whole animals without side effects. Useful as intracellular pH indicator with a wide range of fluorescence (pH 3 to pH 13). pH-dependent dual-emission peaks, can be used for ratiometric […]
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Potent, naturally occuring non-steroid estrogenic compound. Tool to promote mitochondrial calcium overload and to promote calcium-dependent opening of the mitochondrial permeability transition pore (mPTP). Strong agonist for estrogen receptor (ER)alpha and agonist/antagonist for ERbeta. Calcium ionophoretic Apoptosis modulator. Antiproliferative. Increases nitric oxide synthase activity and phosphoinositides breakdown in nervous tissue. Shows aphrodisiac and anti-sexual impotence […]
More Information Supplier PagePotent, naturally occuring non-steroid estrogenic compound. Tool to promote mitochondrial calcium overload and to promote calcium-dependent opening of the mitochondrial permeability transition pore (mPTP). Strong agonist for estrogen receptor (ER)alpha and agonist/antagonist for ERbeta. Calcium ionophoretic Apoptosis modulator. Antiproliferative. Increases nitric oxide synthase activity and phosphoinositides breakdown in nervous tissue. Shows aphrodisiac and anti-sexual impotence […]
More Information Supplier PageMost commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor […]
More Information Supplier PageMost commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor […]
More Information Supplier PageMost commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor […]
More Information Supplier PageMost commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor […]
More Information Supplier PageTingling-inducing agent. Excellent stable model compound for sensory studies. Exerts same profile as the unstable compound hydroxy-alpha-sanshool. Shows larvicidal, antimycobacterial and antituberculosis activity. alpha-Glucosidase inhibitor used in diabetes mellitus, cancer, infection and inflammatory research. ACAT (Acyl-CoA cholesteryl acyl transferase) inhibitor. Potential anti-cancer lead compound. Anti-thrombotic. Anti-septic. Antiprotozoal, antimalarial activity.
More Information Supplier PageTingling-inducing agent. Excellent stable model compound for sensory studies. Exerts same profile as the unstable compound hydroxy-alpha-sanshool. Shows larvicidal, antimycobacterial and antituberculosis activity. alpha-Glucosidase inhibitor used in diabetes mellitus, cancer, infection and inflammatory research. ACAT (Acyl-CoA cholesteryl acyl transferase) inhibitor. Potential anti-cancer lead compound. Anti-thrombotic. Anti-septic. Antiprotozoal, antimalarial activity.
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