AdipoGen Life Sciences
N-Acetyl-D-glucosamine (D-GlcNAc) is a non-toxic derivatized glucose monosaccharide found in polymers (Peptidoglycan; PGN) of bacterial cell walls, chitin (e.g. fungi, invertebrates, crustaceans), hyaluronic acids and various glycans. It is also synthesized in the glycosylation pathway as uridine diphosphate (UDP-GlcNAc), which can then be released following degradation of glycosylated proteins. Atypical microbial danger signal that acts […]
More Information
Supplier Page
AdipoGen Life Sciences
Mycotoxin. Common contaminant in corn and other grains. Hybrid dimer of Blennolide A and B. Cytotoxic anticancer compound. Reported to induce apoptosis by modulating RhoGDI 2 levels in HL60 cells. Protein tyrosine phosphatase 1B (PTP1B) inhibitor (IC50=9.6µM). PTP1B is thought to function as a negative regulator of insulin and leptin signal transduction and therefore being […]
More Information
Supplier Page
AdipoGen Life Sciences
A-Type proanthocyanidine. Potent antioxidant. Free radical scavenger and lipid peroxidation inhibitor. Potent low-density lipoprotein (LDL) oxidation inhibitor. Antidiabetic. Prevents islet cell apoptosis, hyperglycemia and type 2 diabetes through it’s antioxidant properties. Antibacterial agent. Antiviral. Shown to inhibit viral replication of canine distemper virus (CDV). Glycosyltransferase B (GTFB) inhibitor.
More Information
Supplier Page
AdipoGen Life Sciences
Common trichothecene mycotoxin, which can infect grain crops causing alimentary toxic aleukia in humans and animals. Inhibits DNA and RNA synthesis in vivo and in vitro and can induce apoptosis. In vivo the compound rapidly metabolizes to HT-2 mycotoxin (a major metabolite). Inhibits protein synthesis through its high binding affinity to peptidyl transferase, which is […]
More Information
Supplier Page
AdipoGen Life Sciences
Microtubule polymerization inhibitor. Disrupts F-actin and induces nucleophosmin/B23 translocation. Immunomodulator with antimicrobial, anti-inflammatory and antitumorigenic properties. Induces apoptosis, autophagy and cell cycle arrest at G2/M phase in a range of cancer cell lines. Shown to inhibit STAT 3 phosphorylation and expression levels and blocks JAK2 activity, as well as the transcriptional activity of HIF1alpha and […]
More Information
Supplier Page
AdipoGen Life Sciences
Microtubule polymerization inhibitor. Disrupts F-actin and induces nucleophosmin/B23 translocation. Immunomodulator with antimicrobial, anti-inflammatory and antitumorigenic properties. Induces apoptosis, autophagy and cell cycle arrest at G2/M phase in a range of cancer cell lines. Shown to inhibit STAT 3 phosphorylation and expression levels and blocks JAK2 activity, as well as the transcriptional activity of HIF1alpha and […]
More Information
Supplier Page
AdipoGen Life Sciences
Microtubule polymerization inhibitor. Disrupts F-actin and induces nucleophosmin/B23 translocation. Immunomodulator with antimicrobial, anti-inflammatory and antitumorigenic properties. Induces apoptosis, autophagy and cell cycle arrest at G2/M phase in a range of cancer cell lines. Shown to inhibit STAT 3 phosphorylation and expression levels and blocks JAK2 activity, as well as the transcriptional activity of HIF1alpha and […]
More Information
Supplier Page
AdipoGen Life Sciences
Antibiotic. Exhibits broad activity against Gram-positive bacteria. Bacterial cell division protein FtsZ inhibitor (IC50=8.2µg/ml). Inhibits the GTPase activity of FtsZ in vitro (IC50=7.0µg/ml). Induces apoptosis and autophagy and inhibits cell growth at G2/M in human prostate cancer cells. Activates ATP hydrolysis and induces calcium sensitized swelling of rat liver mitochondria.
More Information
Supplier Page
AdipoGen Life Sciences
Potent inhibitor of human 5-lipoxygenase (5-LO). This enzyme catalyzes two initial steps in the conversion of arachidonic acid into leukotrienes, well known mediators of inflammatory and allergic reactions. Iron-chelating compound. Anticancer antibiotic. Shown to inhibit tumor cell invasion in vitro. Antibacterial compound. Antioxidant with free radical scavenging activities.
More Information
Supplier Page
AdipoGen Life Sciences
Potent inhibitor of human 5-lipoxygenase (5-LO). This enzyme catalyzes two initial steps in the conversion of arachidonic acid into leukotrienes, well known mediators of inflammatory and allergic reactions. Iron-chelating compound. Anticancer antibiotic. Shown to inhibit tumor cell invasion in vitro. Antibacterial compound. Antioxidant with free radical scavenging activities.
More Information
Supplier Page
