Fluorogenic substrate for the peptidylglutamyl-peptide hydrolysing (PGPH) (caspase-like) activity of the 20S proteasome. Excitation: 380nm. Emission: 460nm.
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Fluorogenic substrate for the peptidylglutamyl-peptide hydrolysing (PGPH) (caspase-like) activity of the 20S proteasome. Excitation: 380nm. Emission: 460nm.
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Reversible and cell permeable proteasome inhibitor. Specifically inhibits the chymotrypsin-like activity of the proteasome. Calpain and cathepsin inhibitor. Does not inhibit the peptidyl-glutamyl peptide hydrolyzing activity of MPC.
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Selective cell permeable and irreversible MALT1 inhibitor. Inhibits NF-kappaB-dependent gene expression and affects the growth, proliferation and survival of activated B cell-like diffuse large B cell lymphomas (ABC-DLBCL) and germinal center B cell like diffuse large B cell lymphoma (GCB-DLBCL) cell lines. Shown to inhibit the autoprocessing activity of MCA2ac (calcium dependent) in Trypanosoma brucei.
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Cell permeable, non-toxic negative control for the caspase inhibitor Q-VD-OPh (Prod. No. AG-CP3-0006). Stable in aqueous environment. Several folds less inhibitory activity than Q-VD-OPh. Perfect for both in vitro and in vivo studies.
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Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains. Non-toxic due to the 2,6-difluorophenoxy methyl (OPh) group. The peptide is not O-methylated to reduce hydrophobicity and to facilitate use in aqueous media. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy […]
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Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains. Non-toxic due to the 2,6-difluorophenoxy methyl (OPh) group. The peptide is not O-methylated to reduce hydrophobicity and to facilitate use in aqueous media. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy […]
More Information Supplier Page Cell permeable, irreversible and non-toxic non-FMK pan-caspase inhibitor with improved potency, stability and toxicity over Z-VAD-FMK. Does not cross-react with cathepsins nor calpains. Non-toxic due to the 2,6-difluorophenoxy methyl (OPh) group. The peptide is not O-methylated to reduce hydrophobicity and to facilitate use in aqueous media. Inhibits ICE-family protease/caspase processing, leading to apoptosis and autophagy […]
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Potent, selective agonist of µ-opioid receptor. Antinociceptive. Stimulates calcium-activated adenylyl cyclases related cAMP production. Expresses chemokines and chemokine receptors through TGF-beta1. Increases food intake of rats.
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Potent, selective agonist of µ-opioid receptor. Antinociceptive. Stimulates calcium-activated adenylyl cyclases related cAMP production. Expresses chemokines and chemokine receptors through TGF-beta1. Increases food intake of rats.
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