Bisindolylmaleimide IV [Ro 31-6233] 1 mg | >98%
AdipoGen Life Sciences
Cell permeable protein kinase C (PKC) inhibitor. Inhibits also protein kinase A (PKA).
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Cell permeable protein kinase C (PKC) inhibitor. Inhibits also protein kinase A (PKA).
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Potent fluorescent inhibitor of choline acetyltransferase. CMKLR1 antagonist. Inhibits chemerin-stimulated beta-arrestin2 association with CMKLR1, as well as chemerin-triggered CMKLR1+ cell migration. Aldehyde dehydrogenase 1 (ALDH1A1) antagonist.
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Potent fluorescent inhibitor of choline acetyltransferase. CMKLR1 antagonist. Inhibits chemerin-stimulated beta-arrestin2 association with CMKLR1, as well as chemerin-triggered CMKLR1+ cell migration. Aldehyde dehydrogenase 1 (ALDH1A1) antagonist.
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Potent and selective protein kinase C (PKC) inhibitor. Inhibits panel of protein kinases (e.g. GSK-3beta, CDK2).
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Selective and cell permeable protein kinase C (PKC) inhibitor. Inhibits the stimulation of insulin secretion by glucose. Inhibits T cell activation. Apoptosis inducer. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Transcription inhibitor. Induces TNF receptor family-mediated cell death. Pim-1 kinase inhibitor. Antitumor compound.
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Selective and cell permeable protein kinase C (PKC) inhibitor. Inhibits the stimulation of insulin secretion by glucose. Inhibits T cell activation. Apoptosis inducer. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Transcription inhibitor. Induces TNF receptor family-mediated cell death. Pim-1 kinase inhibitor. Antitumor compound.
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Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM). Competitive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Necrosis inhibitor. Blocks hERG potassium channels. Promotes osteoblastogenesis in human mesenchymal stem cells.
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Cell permeable kinase inhibitor with improved selectivity for protein kinase C (PKC) (Ki = 10 nM). Competitive inhibitor for the ATP-binding site of PKC. Anti-inflammatory. Binds to P-glycoprotein. Telomerase activity inhibitor. Potent glycogen synthase kinase-3 (GSK-3) inhibitor. Necrosis inhibitor. Blocks hERG potassium channels. Promotes osteoblastogenesis in human mesenchymal stem cells.
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Selective cell permeable protein kinase C (PKC) inhibitor. G protein-coupled receptor kinase (GRK-5) inhibitor. Less potent GRK-2 or GRK-3 inhibitor. Prevents T cell-driven chronic inflammatory responses in vivo.
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Selective cell permeable protein kinase C (PKC) inhibitor. G protein-coupled receptor kinase (GRK-5) inhibitor. Less potent GRK-2 or GRK-3 inhibitor. Prevents T cell-driven chronic inflammatory responses in vivo.
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