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Reticulol 1 mg  | >98%

AdipoGen Life Sciences

Antibiotic. Cyclic adenosine 3′,5′-monophosphate phosphodiesterase and topoisomerase I (Topo I) inhibitor. Antitumor compound.

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UK-1 250 µg  | >98%

AdipoGen Life Sciences

Antibiotic. Antifungal. Topoisomerase II (Topo II) inhibitor. Mg2+- and Zn2+-dependent DNA binding agent. Potent anticancer compound.

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YM-254890 1 mg  | >95%

AdipoGen Life Sciences

Cyclic depsipeptide composed of unique amino acids differing from normal amino acids. Membrane permeable, potent and selective Galphaq family inhibitor. Inhibits the signal transduction of Galphaq, Galpha11 and Galpha14 (IC50=0.095µM) by blocking the exchange of GDP for GTP, preventing the activation of the G protein. Inhibits platelet aggregation induced by ADP. Shown to inhibit Galphaq-coupled […]

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Me6BIO 25 mg  | >95%

AdipoGen Life Sciences

N-methylated inactive control analog of 6-bromoindirubin-3′-oxime (6BIO) (Prod. No. MR-C0019). Displays minimal activity against CDK1/Cyclin B, GSK-3 alpha/beta and CDK5/p25. Aryl hydrocarbon receptor (AhR) agonist; causes redistribution of AhR to the nucleus.

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Me7BIO 5 mg  | >95%

AdipoGen Life Sciences

N-methylated inactive control compound for 7BIO (Prod. No. MR-C0020). Aryl hydrocarbon receptor (AhR) agonist; causes redistribution of AhR to the nucleus.

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Me7BIO 25 mg  | >95%

AdipoGen Life Sciences

N-methylated inactive control compound for 7BIO (Prod. No. MR-C0020). Aryl hydrocarbon receptor (AhR) agonist; causes redistribution of AhR to the nucleus.

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Leucettine L41 1 mg  | >98%

AdipoGen Life Sciences

Potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3alpha/beta, CK2 and PIM1. Interacts with the complex PIKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against APP-induced cell death. Tools to study and modulate pre-RNA splicing. Potential compound for Alzheimer’s disease and diseases involving abnormal pre-mRNA splicing. Potential compound to study Down […]

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Leucettine L41 5 mg  | >98%

AdipoGen Life Sciences

Potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3alpha/beta, CK2 and PIM1. Interacts with the complex PIKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against APP-induced cell death. Tools to study and modulate pre-RNA splicing. Potential compound for Alzheimer’s disease and diseases involving abnormal pre-mRNA splicing. Potential compound to study Down […]

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Leucettine L41 25 mg  | >98%

AdipoGen Life Sciences

Potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3alpha/beta, CK2 and PIM1. Interacts with the complex PIKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against APP-induced cell death. Tools to study and modulate pre-RNA splicing. Potential compound for Alzheimer’s disease and diseases involving abnormal pre-mRNA splicing. Potential compound to study Down […]

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6-Aminophenanthridine 1 mg  | >97%

AdipoGen Life Sciences

Antiprion agent. Ribosome-borne protein folding activity (RPFA) inhibitor. Binds to the ribosomal RNA and inhibits specifically the protein folding activity of the ribosome. Inhibitor of protein aggregation.

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