Potent, less toxic analog of geldanamycin (Prod. No. BVT-0196). Inhibits the essential ATPase activity of HSP90. Telomerase activity inhibitor. Apoptosis inducer. Antitumor compound.
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Potent, less toxic analog of geldanamycin (Prod. No. BVT-0196). Inhibits the essential ATPase activity of HSP90. Telomerase activity inhibitor. Apoptosis inducer. Antitumor compound.
More Information Supplier Page Potent, less toxic analog of geldanamycin (Prod. No. BVT-0196). Inhibits the essential ATPase activity of HSP90. Telomerase activity inhibitor. Apoptosis inducer. Antitumor compound.
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Antibiotic. Potent antitumor compound. pp60src tyrosine kinase inhibitor. Inhibits c-mycgene expression in murine lymphoblastoma cells. Inhibits the transforming activity of abl, erbB, fps, src and yes. Binds specifically to heat shock protein 90 (HSP90) and to its endoplasmic reticulum homolog GP96 (GRP94). Destabilizes several oncogene and proto-oncogene products. Potent nuclear hormone receptor family inhibitor.
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Antibiotic. Potent antitumor compound. pp60src tyrosine kinase inhibitor. Inhibits c-mycgene expression in murine lymphoblastoma cells. Inhibits the transforming activity of abl, erbB, fps, src and yes. Binds specifically to heat shock protein 90 (HSP90) and to its endoplasmic reticulum homolog GP96 (GRP94). Destabilizes several oncogene and proto-oncogene products. Potent nuclear hormone receptor family inhibitor.
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Antibacterial. Phytotoxin. Melanogenesis inhibitor by reducing tyrosinase production via extracellular signal-regulated protein kinase (ERK) activation. Keratinocyte and epidermis proliferation inhibitor. Mycotoxin. Anti-inflammatory modulator in pulpal inflammation. Angiogenesis inhibitor through angiogenin secretion inhibition. Collagen-induced platelet aggregation inhibitor. Antioxidant agent that enhances osseointegration by decreasing the level of ROS and having a potentially synergistic effect on osteoblast […]
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Antibacterial. Phytotoxin. Melanogenesis inhibitor by reducing tyrosinase production via extracellular signal-regulated protein kinase (ERK) activation. Keratinocyte and epidermis proliferation inhibitor. Mycotoxin. Anti-inflammatory modulator in pulpal inflammation. Angiogenesis inhibitor through angiogenin secretion inhibition. Collagen-induced platelet aggregation inhibitor. Antioxidant agent that enhances osseointegration by decreasing the level of ROS and having a potentially synergistic effect on osteoblast […]
More Information Supplier Page Antibacterial. Phytotoxin. Melanogenesis inhibitor by reducing tyrosinase production via extracellular signal-regulated protein kinase (ERK) activation. Keratinocyte and epidermis proliferation inhibitor. Mycotoxin. Anti-inflammatory modulator in pulpal inflammation. Angiogenesis inhibitor through angiogenin secretion inhibition. Collagen-induced platelet aggregation inhibitor. Antioxidant agent that enhances osseointegration by decreasing the level of ROS and having a potentially synergistic effect on osteoblast […]
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Protein transport from ER to Golgi inhibitor. ADP-ribosylation factor (Arf) inhibitor. Cytotoxic. Antibiotic. Antiviral. Apoptosis inducer. Antitumor compound. Intracellular collagen degradation inhibitor Reviews.
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Mycotoxin. Cytotoxic. Tremorgenic. Potent and specific inhibitor of the breast cancer resistance protein (BCRP; ABCG2). Reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro.
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