AdipoGen Life Sciences
Metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound that functions via inhibiton of cyclooxygenase (COX). Diclofenac undergoes biotransformation not only by glucuronidation, but also by cytochrome P450–mediated oxidation to produce 4′-OH-DFN and 5-OH-DFN, which undergo subsequent oxidation to form highly electrophilic benzoquinone imine intermediates. Compound can be used as analytical reference material.
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AdipoGen Life Sciences
A nicotinic acid analog. Substrate analog MHPCO, used in the investigation of the hydroxylation mechanism of the flaovoprotein 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (MHPCO). Also used as building block for synthesis. Hydroxynicotinic acid is formed by the enzymatic action of nicotinate with nicotinic acid hydroxylase or nicotinate hydroxylase.
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AdipoGen Life Sciences
A nicotinic acid analog. Substrate analog MHPCO, used in the investigation of the hydroxylation mechanism of the flaovoprotein 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase (MHPCO). Also used as building block for synthesis. Hydroxynicotinic acid is formed by the enzymatic action of nicotinate with nicotinic acid hydroxylase or nicotinate hydroxylase.
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AdipoGen Life Sciences
An intermediate and starting material for various coumarin syntheses. Used to prepare aminocoumarins via microwave-accelerated Pechmann reaction or as starting material for coumarin C-ribosides.
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AdipoGen Life Sciences
Keto acid that is involved in the tyrosine catabolism pathway. It is a product of the enzyme (R)-4-hydroxyphenyllactate dehydrogenase and is formed during tyrosine metabolism. The conversion from tyrosine to 4-HPPA is catalyzed by tyrosine aminotransferase. 4-HPPA can be converted to homogentisic acid which is one of the precursors to ochronotic pigment. A deficiency in […]
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AdipoGen Life Sciences
Keto acid that is involved in the tyrosine catabolism pathway. It is a product of the enzyme (R)-4-hydroxyphenyllactate dehydrogenase and is formed during tyrosine metabolism. The conversion from tyrosine to 4-HPPA is catalyzed by tyrosine aminotransferase. 4-HPPA can be converted to homogentisic acid which is one of the precursors to ochronotic pigment. A deficiency in […]
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AdipoGen Life Sciences
A phase transfer catalyst directing enolate alkylation towards O-substitution. Starting material for preparing the corresponding fluoride, a very reactive naked fluoride, with KF.
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AdipoGen Life Sciences
A phase transfer catalyst directing enolate alkylation towards O-substitution. Starting material for preparing the corresponding fluoride, a very reactive naked fluoride, with KF.
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AdipoGen Life Sciences
A phase transfer catalyst directing enolate alkylation towards O-substitution. Starting material for preparing the corresponding fluoride, a very reactive naked fluoride, with KF.
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AdipoGen Life Sciences
7-Hydroxy-4-methyl-2(1H)-quinolone is a starting material for the synthesis of a potential cytotoxic compound class with activity against human tumor cell lines.
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