Triptolide 1 mg | >95%
Creative Biolabs
ADCs cytotoxin, Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii.
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Taltobulin trifluoroacetate 1 mg | >95%
Creative Biolabs
ADCs cytotoxin, Taltobulin trifluoroacetate (HTI-286; SPA-110) is an analogue of Hemiasterlin; potent tubulin inhibitor; ADCs cytotoxin.
More Information Supplier PageTaltobulin 1 mg | >95%
Creative Biolabs
ADCs cytotoxin, Taltobulin (HTI-286; SPA-110) is an analogue of Hemiasterlin; potent tubulin inhibitor; ADCs cytotoxin.
More Information Supplier PagePNU-159682 1 mg | >95%
Creative Biolabs
ADCs cytotoxin, PNU-159682 is a major bioactive metabolite of Nemorubicin in human liver microsomes; > 3,000-fold cytotoxic than its parent compound(MMDX and doxorubicin).
More Information Supplier PageCryptophycin 1 mg | >95%
Creative Biolabs
ADCs Toxins, Cryptophycins are potent microtubule inhibitors, with a mechanism of action similar to that of paclitaxel and vinca alkaloids. Treatment of cells with cryptophycins depletes microtubules through interaction with tubulin, thereby preventing cell division. Cryptophycins are capable of inducing apoptosis, possibly through other mechanisms in addition to that mediated by microtubule inhibition.
More Information Supplier PageDuocarmycin SA 1 mg | >95%
Creative Biolabs
ADCs Toxins, Duocarmycins, which were first isolated from Streptomyces bacteria in 1988, have shown activity in a variety of multi-drug resistant (MDR) models. Agents that are part of this class of duocarmycins have the potency in the low picomolar range. This makes them suitable for maximizing the cell-killing potency of antibody-drug conjugates to which they […]
More Information Supplier PageCurvulin 1 mg | >95%
Creative Biolabs
ADCs Toxins, Curvulin is a phytotoxin. Curvulin is an microtubule assembly inhibitor.
More Information Supplier PageCucurbitacin E 1 mg | >95%
Creative Biolabs
ADCs Toxins, Cucurbitacin E is a tetracyclic triterpene, isolated from cucurbitaceous plants. It has been reported to possess anti-inflammatory and antiproliferative effects mediated by its action on the polymerisation of the actin cytoskeleton. Many cancer preventive properties have been reported. CuE induces cell cycle arrest and apoptosis in human breast cancer cell lines. It promotes […]
More Information Supplier PageCucurbitacin B 1 mg | >95%
Creative Biolabs
ADCs Toxins, Cucurbitacin B is a oxygenated triterpenoid molecule predominantly found in different species of the Cucurbitaceae family. One of its most relevant acticity, is the cytotoxic effects towards human cancer cell lines e.g. breast, lung, prostate, and human colon. A recent study from Marostica et al investigates the synergistic antiproliferative effects of a new […]
More Information Supplier PageCordycepin 1 mg | >95%
Creative Biolabs
ADCs Toxins, Cordycepin from Cordyceps militaris. Cordycepin blocks revovery of non-heat-shock mRNA translation following heat shock in Drosophilla. Antileukemic activity and mechanism of action of cordycepin against terminal deoxynucleotide transferase-positive leukemic cells has been reported. Cordycepin blocks the Smad signaling by 3`-deoxyadenosine (a mechanism for its anti-fibriotic potential).
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