Ambrisentan is an oral, once-daily endothelin receptor antagonist that is selective for the endothelin type A receptor (IC50s = 0.251, 0.316, 0.398, 251, and 630 nM for rat preparations of heart, bladder, kidney, lung, and cerebral cortex, respectively).
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Ambrisentan is an oral, once-daily endothelin receptor antagonist that is selective for the endothelin type A receptor (IC50s = 0.251, 0.316, 0.398, 251, and 630 nM for rat preparations of heart, bladder, kidney, lung, and cerebral cortex, respectively).
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BRL-15572 2HCl is a selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B and exhibiting little or no affinity for a range of other receptor types.
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BRL-15572 2HCl is a selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B and exhibiting little or no affinity for a range of other receptor types.
More Information Supplier Page BRL-15572 2HCl is a selective h5-HT1D antagonist, displaying 60-fold selectivity over h5-HT1B and exhibiting little or no affinity for a range of other receptor types.
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Indole-3-Carbinol is a naturally occuring plant hormone found in cruciferous vegetables, which can both inhibit carcinogenesis in several animal species and enhance tumor incidence if administered at a post-initiation stage.
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Indole-3-Carbinol is a naturally occuring plant hormone found in cruciferous vegetables, which can both inhibit carcinogenesis in several animal species and enhance tumor incidence if administered at a post-initiation stage.
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Disulfiram is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram acts as an allosteric inhibitor of MERS-CoV PLpro but as a competitive (or mixed) inhibitor of SARS-CoV PLpro.
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Disulfiram is a specific inhibitor of aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol. Disulfiram acts as an allosteric inhibitor of MERS-CoV PLpro but as a competitive (or mixed) inhibitor of SARS-CoV PLpro.
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