PD158780, a pyridopyrimidine derivative, is reversible inhibitor of ErbB receptor family (IC50s for EGFR, ErbB2 and ErbB2/ErbB4 are 0.008 nM, 49 nM and 52 nM respectively).
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PD158780, a pyridopyrimidine derivative, is reversible inhibitor of ErbB receptor family (IC50s for EGFR, ErbB2 and ErbB2/ErbB4 are 0.008 nM, 49 nM and 52 nM respectively).
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Vilazodone HCl is both a selective 5-HT reuptake inhibitor and a partial 5-HT1A receptor agonist.
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Vilazodone HCl is both a selective 5-HT reuptake inhibitor and a partial 5-HT1A receptor agonist.
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Gambogic acid activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM, respectively.
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Gambogic acid activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM, respectively.
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Gambogic acid activates caspases with EC50 of 0.78-1.64 μM and competitively inhibits Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 with IC50 of 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μM, respectively.
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