IOX1 1mg | ≥99%
CSNpharm
IOX1 is the broad-spectrum inhibitor of 2OG oxygenases and its IC50 for KDM4A/KDM3A and KDM4C/KDM6B/KDM2A/KDM4E are 0.6/0.1 μM and 0.6 μM/1.6 μM/1.8 μM/2.3 μM.
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IOX1 is the broad-spectrum inhibitor of 2OG oxygenases and its IC50 for KDM4A/KDM3A and KDM4C/KDM6B/KDM2A/KDM4E are 0.6/0.1 μM and 0.6 μM/1.6 μM/1.8 μM/2.3 μM.
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IOX1 is the broad-spectrum inhibitor of 2OG oxygenases and its IC50 for KDM4A/KDM3A and KDM4C/KDM6B/KDM2A/KDM4E are 0.6/0.1 μM and 0.6 μM/1.6 μM/1.8 μM/2.3 μM.
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PSI-6206, the deaminated derivative of PSI-6130, is a selective inhibitor of HCV NS5B polymerase and the EC50 for inhibition of HCV replicon is > 100 μM.
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Paroxetine HCl is a selective serotonin-reuptake inhibitor (SSRI) with antidepressant activity.
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Clevidipine is a short-acting dihydropyridine calcium channel antagonist with IC50 of 7.1 nM, it’s under development for treatment of perioperative hypertension.
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Ropinirole HCl selectively inhibit dopamine D2 receptor with Ki of 29 nM. It is used for the treatment of spontaneous parkinson’s disease.
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4-Methylumbelliferone, a natural product isolated and purified from the herbs of Ruta graveolens L., is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM.
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4-Methylumbelliferone, a natural product isolated and purified from the herbs of Ruta graveolens L., is a hyaluronic acid (HA) synthesis inhibitor with an IC50 of 0.4 mM.
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Furan-2-carboxylic acid, a natural product isolated and purified from the herbs of Hexagonia speciosa with anti-bacterial effect, is also an orally active selective human cathepsin K inhibitor which may have the therapeutic potential for the treatment of diseases characterized by excessive bone loss including osteoporosis.
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Salicylanilides can inhibit HIV-1 integrase or reverse transcriptase with potent antiviral activity.
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