β-thujaplicin can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity of metallothionein induced by the agent. Also, β-Thujaplicin modulates estrogen receptor signaling and inhibits proliferation of human breast cancer cells.
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2, 6-dimethoxy-1, 4-benzoquinone is a member of the class of compounds known as P-benzoquinones. 2, 6-dimethoxy-1, 4-benzoquinone is slightly soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). It is a benzoquinone, a chemical compound found in Rauvolfia vomitoria, in Tibouchina pulchra, and in common wheat.
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WAY-200070 is a specific agonist of estrogen receptor β (ERRβ, IC50: 2.3 nM).
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PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.
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B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor.
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B7/CD28 interaction inhibitor 1 (CTLA-4 inhibitor) is a potent CTLA-4 inhibitor.
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MLN1117 (INK1117) is a p110α/β/γ/δ inhibitor (IC50: 15/4.5/1.9/13.39 μM).
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UNC1999 is a orally bioavailable, effective and specific inhibitor of EZH2 (IC50=2 nM) and EZH1 (IC50=45).
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PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.
More Information Supplier Page PF-4136309 (INCB8761) is a specific, effective, and orally bioavailable CCR2 antagonist.
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