JZL184 50mg | Purity Not Available
Selleck Chemicals
JZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM.
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SN-38 50mg | Purity Not Available
Selleck Chemicals
SN-38 (NK012) is an active metabolite of CPT-11, inhibits DNA topoisomerase I, DNA synthesis and causes frequent DNA single-strand breaks. SN-38 induces autophagy.
More Information Supplier Page(R)-Nepicastat HCl 10mg | Purity Not Available
Selleck Chemicals
(R)-Nepicastat HCl (RS-25560-198), the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
More Information Supplier PageAtaluren (PTC124) 10mg | Purity Not Available
Selleck Chemicals
Ataluren (PTC124) selectively induces ribosomal read-through of premature but not normal termination codons, with EC50 of 0.1 μM in HEK293 cells, may provide treatment for genetic disorders caused by nonsense mutations (e.g. CF caused by CFTR nonsense mutation). Phase 3.
More Information Supplier PageAtaluren (PTC124) 10mM/1mL | Purity Not Available
Selleck Chemicals
Ataluren (PTC124) selectively induces ribosomal read-through of premature but not normal termination codons, with EC50 of 0.1 μM in HEK293 cells, may provide treatment for genetic disorders caused by nonsense mutations (e.g. CF caused by CFTR nonsense mutation). Phase 3.
More Information Supplier PageDuvelisib (IPI-145) 5mg | Purity Not Available
Selleck Chemicals
Duvelisib (IPI-145, INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM in cell-free assays, highly selective for PI3K δ/γ than other protein kinases. Phase 3.
More Information Supplier PageDuvelisib (IPI-145) 50mg | Purity Not Available
Selleck Chemicals
Duvelisib (IPI-145, INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM in cell-free assays, highly selective for PI3K δ/γ than other protein kinases. Phase 3.
More Information Supplier PageDuvelisib (IPI-145) 10mM/1mL | Purity Not Available
Selleck Chemicals
Duvelisib (IPI-145, INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM in cell-free assays, highly selective for PI3K δ/γ than other protein kinases. Phase 3.
More Information Supplier PageNMDA (N-Methyl-D-aspartic acid) 50mg | Purity Not Available
Selleck Chemicals
NMDA（N-Methyl-D-aspartic acid）is a specific agonist for NMDA receptor mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Phase 4.
More Information Supplier PageHydroxychloroquine (HCQ) Sulfate 50mg | Purity Not Available
Selleck Chemicals
Hydroxychloroquine (HCQ) Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9.
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