Selleck Chemicals
Ritanserin (R 55667) is a highly potent, selective, orally active, and long-acting antagonist of 5-HT2 receptor with an IC50 of 0.9 nM. It exhibits minimal activity at H1, D2, and adrenergic receptors and enhances midbrain dopamine neuron activity by blocking 5-HT2-mediated inhibition.
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Selleck Chemicals
Ritanserin (R 55667) is a highly potent, selective, orally active, and long-acting antagonist of 5-HT2 receptor with an IC50 of 0.9 nM. It exhibits minimal activity at H1, D2, and adrenergic receptors and enhances midbrain dopamine neuron activity by blocking 5-HT2-mediated inhibition.
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FLT3-IN-3
25mg
| Purity Not Available
Selleck Chemicals
FLT3-IN-3 is a potent inhibitor of FLT3 with IC50 values of 13 nM and 8 nM for FLT3 WT and FLT3 D835Y, respectively. FLT3-IN-3 effectively suppresses the proliferation of FLT3-ITD-positive MV4-11 and MOLM-13 cell lines at low nanomolar concentrations.
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Selleck Chemicals
Selenomethionine (Seleno-DL-methionine, DL-Selenomethionine) is a naturally occurring amino acid containing selenium. Selenomethionine (SeMet) can substitute for methionine (Met) during protein synthesis in a non-specific manner. Due to the significant differences in their redox properties, the incorporation of SeMet in place of Met may adversely impact protein function.
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FLT3-IN-3
5mg
| Purity Not Available
Selleck Chemicals
FLT3-IN-3 is a potent inhibitor of FLT3 with IC50 values of 13 nM and 8 nM for FLT3 WT and FLT3 D835Y, respectively. FLT3-IN-3 effectively suppresses the proliferation of FLT3-ITD-positive MV4-11 and MOLM-13 cell lines at low nanomolar concentrations.
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Selleck Chemicals
Tacrolimus monohydrate (Tacrolimus, FK506) is a macrolide antibiotic that primarily acts as an inhibitor of calcineurin phosphatase by binding to FK506 binding protein (FKBP). This inhibition blocks calcium-dependent processes, including interleukin-2 gene transcription, nitric oxide synthase activation, cell degranulation, and apoptosis, and also has immunosuppressive, neuroregenerative and neuroprotective properties.
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Selleck Chemicals
Tacrolimus monohydrate (Tacrolimus, FK506) is a macrolide antibiotic that primarily acts as an inhibitor of calcineurin phosphatase by binding to FK506 binding protein (FKBP). This inhibition blocks calcium-dependent processes, including interleukin-2 gene transcription, nitric oxide synthase activation, cell degranulation, and apoptosis, and also has immunosuppressive, neuroregenerative and neuroprotective properties.
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Selleck Chemicals
Selenomethionine (Seleno-DL-methionine, DL-Selenomethionine) is a naturally occurring amino acid containing selenium. Selenomethionine (SeMet) can substitute for methionine (Met) during protein synthesis in a non-specific manner. Due to the significant differences in their redox properties, the incorporation of SeMet in place of Met may adversely impact protein function.
More Information
Supplier Page
Selleck Chemicals
Tacrolimus monohydrate (Tacrolimus, FK506) is a macrolide antibiotic that primarily acts as an inhibitor of calcineurin phosphatase by binding to FK506 binding protein (FKBP). This inhibition blocks calcium-dependent processes, including interleukin-2 gene transcription, nitric oxide synthase activation, cell degranulation, and apoptosis, and also has immunosuppressive, neuroregenerative and neuroprotective properties.
More Information
Supplier Page
Selleck Chemicals
Tacrolimus monohydrate (Tacrolimus, FK506) is a macrolide antibiotic that primarily acts as an inhibitor of calcineurin phosphatase by binding to FK506 binding protein (FKBP). This inhibition blocks calcium-dependent processes, including interleukin-2 gene transcription, nitric oxide synthase activation, cell degranulation, and apoptosis, and also has immunosuppressive, neuroregenerative and neuroprotective properties.
More Information
Supplier Page