Cevimeline hydrochloride hemihydrate is a novel muscarinic receptor agonist, used as a candidate therapeutic drug for xerostomia in Sjogren’s syndrome.
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Ipragliflozin is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.
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Tezacaftor (VX661) is a small molecule that can be used as a corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) gene function.
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IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.
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IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.
More Information Supplier Page IM-12, an effective GSK-3β inhibitor(IC50=53 nM), regulates Wnt signalling.
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ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CREB)-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.
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ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CREB)-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.
More Information Supplier Page ICG-001 antagonizes Wnt/β-catenin/TCF-mediated transcription and specifically binds to element-binding protein (CREB)-binding protein (CBP) with IC50 of 3 μM, but is not the related transcriptional coactivator p300.
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8-Azaguanine is a purine analogue with potential antineoplastic activity.
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