Daphnetin is a coumarin analog that acts as an inhibitor of several protein kinases. It inhibits EGFR kinase (IC50 = 7.67 ??M), PKA (IC50 = 9.33 ??M), and PKC (IC50 = 25 ??M), in vitro. The inhibition of EGFR kinase by daphnetin was competitive to ATP and non-competitive to the peptide substrate. Also acts as […]
More Information Supplier PageDaphnetin is a coumarin analog that acts as an inhibitor of several protein kinases. It inhibits EGFR kinase (IC50 = 7.67 ??M), PKA (IC50 = 9.33 ??M), and PKC (IC50 = 25 ??M), in vitro. The inhibition of EGFR kinase by daphnetin was competitive to ATP and non-competitive to the peptide substrate. Also acts as […]
More Information Supplier PageDaphnetin is a coumarin analog that acts as an inhibitor of several protein kinases. It inhibits EGFR kinase (IC50 = 7.67 ??M), PKA (IC50 = 9.33 ??M), and PKC (IC50 = 25 ??M), in vitro. The inhibition of EGFR kinase by daphnetin was competitive to ATP and non-competitive to the peptide substrate. Also acts as […]
More Information Supplier PageDaphnetin is a coumarin analog that acts as an inhibitor of several protein kinases. It inhibits EGFR kinase (IC50 = 7.67 ??M), PKA (IC50 = 9.33 ??M), and PKC (IC50 = 25 ??M), in vitro. The inhibition of EGFR kinase by daphnetin was competitive to ATP and non-competitive to the peptide substrate. Also acts as […]
More Information Supplier PageDapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.
More Information Supplier PageDapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.
More Information Supplier PageDapagliflozin inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.
More Information Supplier PageCytarabine inhibits DNA replication by incorporating into DNA (IC50 = 0.04 ??M in L1210 and CEM cell lines).
More Information Supplier PageCytarabine inhibits DNA replication by incorporating into DNA (IC50 = 0.04 ??M in L1210 and CEM cell lines).
More Information Supplier PageCYT997 is a novel anti-cancer vascular disrupting agent (VDA). In vitro, CYT997 is shown to potently inhibit the proliferation of vascular endothelial growth factor-stimulated human umbilical vein endothelial cells (IC(50) 3.7 ?? 1.8 nM) and cause significant morphological changes at 100 nM, including membrane blebbing.
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