Artemisinin 10mM/1mL | Purity Not Available
Selleck Chemicals
Artemisinin is a sesquiterpene endoperoxide which is a potent antimalarial agent.
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Aniracetam 50mg | Purity Not Available
Selleck Chemicals
IC-87114 5mg | Purity Not Available
Selleck Chemicals
IC-87114 is a selective PI3Kδ inhibitor with IC50 of 0.5 μM in a cell-free assay, 58-fold more selective for PI3Kδ than PI3Kγ, and over 100-fold more selective than PI3Kα/β.
More Information Supplier PageBX-912 5mg | Purity Not Available
Selleck Chemicals
BX912 is a potent and specific PDK1 inhibitor with IC50 of 12 nM, 9- and 105- fold greater selectivity for PDK1 than PKA and PKC in cell-free assays, respectively. In comparison to GSK3β, selectivity for PDK1 is 600-fold.
More Information Supplier PageAdapalene 25mg | Purity Not Available
Selleck Chemicals
Adapalene (CD-271) is a dual RAR and RXR agonist, used in the treatment of acne.
More Information Supplier PageAvagacestat (BMS-708163) 5mg | Purity Not Available
Selleck Chemicals
Avagacestat (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.
More Information Supplier PageAvagacestat (BMS-708163) 50mg | Purity Not Available
Selleck Chemicals
Avagacestat (BMS-708163) is a potent, selective, orally bioavailable γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, demonstrating a 193-fold selectivity against Notch. Phase 2.
More Information Supplier PagePD173074 50mg | Purity Not Available
Selleck Chemicals
PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src. PD173074 reduces proliferation and promotes apoptosis in gastric cancer cells.
More Information Supplier PagePD173074 10mM/1mL | Purity Not Available
Selleck Chemicals
PD173074 is a potent FGFR1 inhibitor with IC50 of ~25 nM and also inhibits VEGFR2 with IC50 of 100-200 nM in cell-free assays, ~1000-fold selective for FGFR1 than PDGFR and c-Src. PD173074 reduces proliferation and promotes apoptosis in gastric cancer cells.
More Information Supplier PageVemurafenib (PLX4032) 10mg | Purity Not Available
Selleck Chemicals
Vemurafenib (PLX4032, RG7204, RO5185426) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM in cell-free assay. 10-fold selective for B-RafV600E over wild-type B-Raf in enzymatic assays and the cellular selectivity can exceed 100-fold. Vemurafenib (PLX4032, RG7204) induces autophagy.
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