PIK-75 is an imidazopyridine that selectively inhibits p110?? with an IC50 value of 5.8 nM.2 It inhibits p110?? and p110?? considerably less effectively with IC50 values of 0.076 ??M and 1.3 ??M, respectively.

PIK-75 is an imidazopyridine that selectively inhibits p110?? with an IC50 value of 5.8 nM.2 It inhibits p110?? and p110?? considerably less effectively with IC50 values of 0.076 ??M and 1.3 ??M, respectively.

PIK-75 is an imidazopyridine that selectively inhibits p110?? with an IC50 value of 5.8 nM.2 It inhibits p110?? and p110?? considerably less effectively with IC50 values of 0.076 ??M and 1.3 ??M, respectively.

PIK-294 is a PI3 Kinase inhibitor that is 20- to 60-fold more potent than the parent compound, PIK-293. It is one of the most potent p110??-selective inhibitors that has been reported.

PIK-294 is a PI3 Kinase inhibitor that is 20- to 60-fold more potent than the parent compound, PIK-293. It is one of the most potent p110??-selective inhibitors that has been reported.

PIK-90 is a synthetic phosphoinositide 3-kinase (PI3K) inhibitor with IC50 values (nM) of 11, 350, 18, and 58 for p110 ??, ??, ?? and ?? isoforms, low mTOR activity.

PIK-90 is a synthetic phosphoinositide 3-kinase (PI3K) inhibitor with IC50 values (nM) of 11, 350, 18, and 58 for p110 ??, ??, ?? and ?? isoforms, low mTOR activity.