LY 379268 is a highly selective group II mGlu receptor agonist (EC50 values are 2.69 and 4.48 nM for hmGlu2 and hmGlu3 respectively) that displays > 80-fold selectivity over group I and group III receptors.
More Information Supplier PageLY 379268 is a highly selective group II mGlu receptor agonist (EC50 values are 2.69 and 4.48 nM for hmGlu2 and hmGlu3 respectively) that displays > 80-fold selectivity over group I and group III receptors.
More Information Supplier PageAmsilarotene (TAC-101) is a retinobenzoic acid with potential antineoplastic activity.
More Information Supplier PageAmsilarotene (TAC-101) is a retinobenzoic acid with potential antineoplastic activity.
More Information Supplier PageAmsilarotene (TAC-101) is a retinobenzoic acid with potential antineoplastic activity.
More Information Supplier PageAmsilarotene (TAC-101) is a retinobenzoic acid with potential antineoplastic activity.
More Information Supplier PagePF-04447943 is a potent, selective brain penetrant PDE9 inhibitor that increased indicators of hippocampal synaptic plasticity and improved cognitive function in a variety of cognition models in both rats and mice.
More Information Supplier PageGSK343 is a potent histone H3-lysine 27 (H3K27) methyltransferase EZH2 inhibitor (IC= 4 nM). Diplays 1000-fold selectivity for other HMTs except EZH1 (60-fold selectivity). GSK343 inhibits H3K27 methylation in HCC1806 cells with an IC of
More Information Supplier PageGSK343 is a potent histone H3-lysine 27 (H3K27) methyltransferase EZH2 inhibitor (IC= 4 nM). Diplays 1000-fold selectivity for other HMTs except EZH1 (60-fold selectivity). GSK343 inhibits H3K27 methylation in HCC1806 cells with an IC of
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