Isoniazid is a prodrug that blocks the action of fatty acid synthase by interacting with KatG , used for the prevention and treatment of tuberculosis.

Haloperidol (Haldol) is an antipsychotic and butyrophenone.

Clofibrate (Atromid-S), a fibric acid derivative used in the treatment of hyperlipoproteinemia type III and severe hypertriglyceridemia.

Tranexamic Acid(Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

Diethylstilbestrol (Stilbestrol) is a synthetic nonsteroidal estrogen, used to prevent miscarriage and other pregnancy complications.Diethylstilbestrol can be used to induce animal models of Pituitary Adenoma.

Dienestrol(Restrol) is a synthetic, non-steroidal estrogen. It is an estrogen receptor agonist.

Penicillamine (Dimethyl Cysteine) is used as an antirheumatic and as a chelating agent in Wilson’s disease.

Penicillamine (Dimethyl Cysteine) is used as an antirheumatic and as a chelating agent in Wilson’s disease.

Daidzein is a natural isoflavone phytoestrogen found in Leguminosae, used as a component of foods and dietary supplements. Daidzein is a soy isoflavone, which acts as a PPAR activator.

Curcumin (Diferuloylmethane, Natural Yellow 3, Turmeric yellow) is the principal curcuminoid of the popular Indian spice turmeric, which is a member of the ginger family (Zingiberaceae). It is an inhibitor of p300 histone acetylatransferase（IC50~25 μM）and Histone deacetylase (HDAC); activates Nrf2 pathway and supresses the activation of NF-κB. Curcumin induces mitophagy, autophagy, apoptosis, and cell cycle […]