SR1001 is a RORα inverse agonist with Ki values of 172 nM and 111 nM for RORα and RORγ respectively.

SR1001 is a RORα inverse agonist with Ki values of 172 nM and 111 nM for RORα and RORγ respectively.

PCI 29732 is a selective and irreversible Btk inhibitor with an IC50 of 0.5 nM.

PCI 29732 is a selective and irreversible Btk inhibitor with an IC50 of 0.5 nM.

AX-024 HCl blocks the interaction of the CD3ε PRS with SH3.1(Nck). AX-024 HCl also inhibits IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.

IDO-IN-1 is a potent indoleamine 2,3-dioxygenase (IDO) inhibitor with an IC50 of 59 nM.

Besifovir is novel and potent acyclic nucleotide phosphonate used to treat hepatitis B virus (HBV) infection.

CC-401 is a potent inhibitor of JNK with at least 40-fold selectivity against other related kinases.

CC-401 is a potent inhibitor of JNK with at least 40-fold selectivity against other related kinases.

Eliprodil (SL-820715) is a non-competitive NR2B-selective NMDA antagonist with IC50 value of 1 μM and is less potent for NR2A- and NR2C-containing receptors with IC50 > 100 μM.