Selleck Chemicals
Disodium (R)-2-Hydroxyglutarate (D-α-Hydroxyglutaric acid disodium) is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 10.87 ± 1.85 mM.
More Information
Supplier Page
CC-115
5mg
| Purity Not Available
Selleck Chemicals
CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR) with IC50 values of 0.013 μM and 0.021 μM, respectively. It has potential antineoplastic activity.
More Information
Supplier Page
CC-115
25mg
| Purity Not Available
Selleck Chemicals
CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR) with IC50 values of 0.013 μM and 0.021 μM, respectively. It has potential antineoplastic activity.
More Information
Supplier Page
Dp44mT
50mg
| Purity Not Available
Selleck Chemicals
Dp44mT
10mg
| Purity Not Available
Selleck Chemicals
PFI-4
10mg
| Purity Not Available
Selleck Chemicals
3′,3′-cGAMP
1mg
| Purity Not Available
Selleck Chemicals
3′,3′-cGAMP (3′,3′-cyclic GMP-AMP, Cyclic GMP-AMP, cGAMP) activates the endoplasmic reticulum (ER)-resident receptor stimulator of interferon genes (STING), thereby inducing an antiviral state and the secretion of type I IFNs.
More Information
Supplier Page
Selleck Chemicals
2′,3′-cGAMP Sodium Salt (2′-3′-cyclic GMP-AMP Sodium) is produced in response to DNA in the cytoplasm in mammalian cells and binds STING with high affinity and is an effective inducer of interferon-β (IFNβ). 2′,3′-cGAMP binds to STING with Kd of 3.79 nM.
More Information
Supplier Page
Ac-DEVD-CHO
25mg
| Purity Not Available
Selleck Chemicals
Ac-DEVD-CHO (Caspase-3 Inhibitor I, N-Ac-Asp-Glu-Val-Asp-CHO) is a potent aldehyde inhibitor of Group II caspases with Ki values of 0.2 nM and 0.3 nM for for caspase-3 and caspase-7, respectively. Weak inhibition for caspase-2.
More Information
Supplier Page
Ac-DEVD-CHO
5mg
| Purity Not Available
Selleck Chemicals
Ac-DEVD-CHO (Caspase-3 Inhibitor I, N-Ac-Asp-Glu-Val-Asp-CHO) is a potent aldehyde inhibitor of Group II caspases with Ki values of 0.2 nM and 0.3 nM for for caspase-3 and caspase-7, respectively. Weak inhibition for caspase-2.
More Information
Supplier Page