VIT-2763 is an oral small-molecule inhibitor of ferroportin. It displaces TMR-hepcidin from ferroportin with an IC50 of 24 nM. It also ameliorates anemia, enhances erythropoiesis, and reduces organ iron loading in the Hbbth3/+ β-thalassemia intermedia disease model.

ZD7288 (ICI D7288) is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker.

Helenalin is an anti-inflammatory sesquiterpene lactone. Helenalin selectively inhibits transcription factor NF-κB by directly targeting p65. Helenalin has alkylating activity, targets the cysteine sulfhydryl groups in the p65 subunit of NF-κB, thereby inhibits its DNA binding.

L-AP4 (L-APB) is a potent and specific agonist for the group III mGluRs, with EC50s of 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6 and mGlu7 receptors, respectively.

Vaborbactam (RPX7009) is a cyclic boronic acid pharmacophore β-lactamase inhibitor.

(R)-CPP is a highly potent NMDA receptor antagonist.

Oligomycin is a macrolide antibiotic produced by Streptomyces. It is a mixture of three oligomycin isomers, namely Oligomycin A, B and C. Oligomycin is an inhibitor of mitochondrial F0 subunit H+-ATP synthase, which can disrupt oxidative phosphorylation and the electron transport chain. It can inhibit TNF-induced apoptosis and can be used as an antifungal antibiotic.

CAY10566 is a potent, orally bioavailable and selective inhibitor of stearoyl-CoA desaturase1 (SCD1) with IC50 of 4.5 and 26 nM in mouse and human enzymatic assays, respectively. It also demonstrates excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells.

CAY10566 is a potent, orally bioavailable and selective inhibitor of stearoyl-CoA desaturase1 (SCD1) with IC50 of 4.5 and 26 nM in mouse and human enzymatic assays, respectively. It also demonstrates excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells.

CAY10566 is a potent, orally bioavailable and selective inhibitor of stearoyl-CoA desaturase1 (SCD1) with IC50 of 4.5 and 26 nM in mouse and human enzymatic assays, respectively. It also demonstrates excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells.