JWG-071 is the kinase-selective chemical probe for ERK5. JWG-071 inhibits ERK5 and LRRK2 with IC50 values of 88nM and 109 nM, respectively.

BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ with IC50 values of 4.6 nM and 2.1 nM, respectively. BMS-502 also exhibits an EC50 value of 340 nM in the mouse cytotoxic T cell IFN-γ assay (mCTC). BMS-502 can be used in tumor immunity-related research.

BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ with IC50 values of 4.6 nM and 2.1 nM, respectively. BMS-502 also exhibits an EC50 value of 340 nM in the mouse cytotoxic T cell IFN-γ assay (mCTC). BMS-502 can be used in tumor immunity-related research.

BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ with IC50 values of 4.6 nM and 2.1 nM, respectively. BMS-502 also exhibits an EC50 value of 340 nM in the mouse cytotoxic T cell IFN-γ assay (mCTC). BMS-502 can be used in tumor immunity-related research.

BMS-502 is a potent dual inhibitor of diacylglycerol kinase (DGK) α and ζ with IC50 values of 4.6 nM and 2.1 nM, respectively. BMS-502 also exhibits an EC50 value of 340 nM in the mouse cytotoxic T cell IFN-γ assay (mCTC). BMS-502 can be used in tumor immunity-related research.

PROTAC tubulin-Degrader-1(compound W13) is an inhibitor of PROTAC tubulin exhibiting antitumor activity against human lung cancer.

PROTAC tubulin-Degrader-1(compound W13) is an inhibitor of PROTAC tubulin exhibiting antitumor activity against human lung cancer.

PROTAC tubulin-Degrader-1(compound W13) is an inhibitor of PROTAC tubulin exhibiting antitumor activity against human lung cancer.

PROTAC tubulin-Degrader-1(compound W13) is an inhibitor of PROTAC tubulin exhibiting antitumor activity against human lung cancer.

A-967079 is a selective antagonist of TRPA1 receptor with IC50 values of 67 nM and 289 nM at human and rat TRPA1 receptors, respectively. A-967079 decreases the responses of wide dynamic range (WDR), and nociceptive specific (NS) neurons following noxious pinch stimulation and high-intensity mechanical stimulation in rats. It demonstrates strong penetration into the central […]