B102(PARP/HDAC-IN-1) is a dual inhibitor of PARP and HDAC, with IC50 of 19.01 nM, 2.13 nM, 1.69 μM, > 10 μM for PARP1, PARP2, HDAC1, HDAC6, respectively, in an enzymatic assay. It exhibits anti-proliferative and anti-tumor effects. It also induces DNA damage and apoptosis in vitro.

B102(PARP/HDAC-IN-1) is a dual inhibitor of PARP and HDAC, with IC50 of 19.01 nM, 2.13 nM, 1.69 μM, > 10 μM for PARP1, PARP2, HDAC1, HDAC6, respectively, in an enzymatic assay. It exhibits anti-proliferative and anti-tumor effects. It also induces DNA damage and apoptosis in vitro.

B102(PARP/HDAC-IN-1) is a dual inhibitor of PARP and HDAC, with IC50 of 19.01 nM, 2.13 nM, 1.69 μM, > 10 μM for PARP1, PARP2, HDAC1, HDAC6, respectively, in an enzymatic assay. It exhibits anti-proliferative and anti-tumor effects. It also induces DNA damage and apoptosis in vitro.

B102(PARP/HDAC-IN-1) is a dual inhibitor of PARP and HDAC, with IC50 of 19.01 nM, 2.13 nM, 1.69 μM, > 10 μM for PARP1, PARP2, HDAC1, HDAC6, respectively, in an enzymatic assay. It exhibits anti-proliferative and anti-tumor effects. It also induces DNA damage and apoptosis in vitro.

AY 9944 is a potent and specific inhibitor of cholesterol biosynthesis, it inhibits the Δ7-sterol reductase with an IC50 of 13 nM. It can be used in the research to study Smith–Lemli–Opitz syndrome, a frequent inborn disorder of sterol metabolism.

TASIN-30 is a selective inhibitor of Emopamil binding protein (EBP) with EC50 values of 0.097 μM for EBP competition, respectively. TASIN-30 displays selectivity for EBP over DHCR24.

TASIN-30 is a selective inhibitor of Emopamil binding protein (EBP) with EC50 values of 0.097 μM for EBP competition, respectively. TASIN-30 displays selectivity for EBP over DHCR24.

TASIN-30 is a selective inhibitor of Emopamil binding protein (EBP) with EC50 values of 0.097 μM for EBP competition, respectively. TASIN-30 displays selectivity for EBP over DHCR24.

TASIN-30 is a selective inhibitor of Emopamil binding protein (EBP) with EC50 values of 0.097 μM for EBP competition, respectively. TASIN-30 displays selectivity for EBP over DHCR24.

HRO761 is a potent, selective, allosteric inhibitor of Werner syndrome RecQ helicase (WRN). It binds at the interface of the D1 and D2 helicase domains, locking WRN in an inactive conformation, and demonstrates anti-proliferative effects specifically in microsatellite instability (MSI) cancer cells.