Potrasertib (IMP7068, WEE1-IN-10) is a potent and selective inhibitor of WEE1 Kinase. It displays antitumor activity and is well-tolerated in patients with advanced solid tumors.

Potrasertib (IMP7068, WEE1-IN-10) is a potent and selective inhibitor of WEE1 Kinase. It displays antitumor activity and is well-tolerated in patients with advanced solid tumors.

COH34 is a potent and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG) with an IC50 value of 0.37 nM. It binds to the catalytic domain of PARG with Kd of 0.547 μM thereby prolonging PARylation at DNA lesions and trapping DNA repair factors and can be used in research of cancer therapies.

Potrasertib (IMP7068, WEE1-IN-10) is a potent and selective inhibitor of WEE1 Kinase. It displays antitumor activity and is well-tolerated in patients with advanced solid tumors.

COH34 is a potent and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG) with an IC50 value of 0.37 nM. It binds to the catalytic domain of PARG with Kd of 0.547 μM thereby prolonging PARylation at DNA lesions and trapping DNA repair factors and can be used in research of cancer therapies.

COH34 is a potent and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG) with an IC50 value of 0.37 nM. It binds to the catalytic domain of PARG with Kd of 0.547 μM thereby prolonging PARylation at DNA lesions and trapping DNA repair factors and can be used in research of cancer therapies.

COH34 is a potent and specific inhibitor of poly(ADP-ribose) glycohydrolase (PARG) with an IC50 value of 0.37 nM. It binds to the catalytic domain of PARG with Kd of 0.547 μM thereby prolonging PARylation at DNA lesions and trapping DNA repair factors and can be used in research of cancer therapies.

MeAIB (α-(Methylamino)isobutyric acid) is a specific substrate for amino acid transport system A, especially System A (ATA1). It also inhibits SNAT2, which reduces intracellular levels of essential amino acids and impairs cell proliferation in porcine enterocytes by disrupting the mTOR signalling pathway.

2-NP (2-(1,8-Naphthyridin-2-yl)phenol) is a selective enhancer of STAT1 transcription. It enhances the antiproliferative effects of IFN-γ on human breast cancer and fibrosarcoma cells.

MeAIB (α-(Methylamino)isobutyric acid) is a specific substrate for amino acid transport system A, especially System A (ATA1). It also inhibits SNAT2, which reduces intracellular levels of essential amino acids and impairs cell proliferation in porcine enterocytes by disrupting the mTOR signalling pathway.