Nigericin is an antibiotic derived from Streptomyces hygroscopicus that acts as a K+/H+ ionophore, which causes the efflux of potassium from the cell and, thus, influences the mitochondria membrane potential. It also induces pyroptosis in macrophages by activating NLRP3 inflammasome.

Carboxy-PTIO potassium is a potent nitric oxide (NO) scavenger that can make a quick reaction with NO to produce NO2. Carboxy-PTIO potassium can prevent hypotension and endotoxic shock through the direct scavenging action against NO in lipopolysaccharide-stimulated rat model.

Etomoxir ((R)-(+)-Etomoxir) is an irreversible, small-molecule inhibitor of carnitine palmitoyl-transferase 1a (CPT1a). It inhibits fatty acid oxidation (FAO) and may have potential in treating diabetes, inflammation, cancer and cardiac metabolic diseases.

BAP1-IN-1 is a small-molecule inhibitor of BRCA1 associated protein 1 (BAP1) catalytic activity in vitro with an IC50 of 0.1-1 μM. It exhibits a potential therapeutic target for leukemia.

BAP1-IN-1 is a small-molecule inhibitor of BRCA1 associated protein 1 (BAP1) catalytic activity in vitro with an IC50 of 0.1-1 μM. It exhibits a potential therapeutic target for leukemia.

BAP1-IN-1 is a small-molecule inhibitor of BRCA1 associated protein 1 (BAP1) catalytic activity in vitro with an IC50 of 0.1-1 μM. It exhibits a potential therapeutic target for leukemia.

BAP1-IN-1 is a small-molecule inhibitor of BRCA1 associated protein 1 (BAP1) catalytic activity in vitro with an IC50 of 0.1-1 μM. It exhibits a potential therapeutic target for leukemia.

STL127705 is a potent small molecule inhibitor of Ku70/80 heterodimer protein with an IC50 of 3.5 μM. It disrupts Non-Homologous End-Joining (NHEJ) by preventing DNA binding and inhibiting DNA-PKCS activation. It exhibits anticancer activity by inducing apoptosis and inhibiting cell proliferation.

STL127705 is a potent small molecule inhibitor of Ku70/80 heterodimer protein with an IC50 of 3.5 μM. It disrupts Non-Homologous End-Joining (NHEJ) by preventing DNA binding and inhibiting DNA-PKCS activation. It exhibits anticancer activity by inducing apoptosis and inhibiting cell proliferation.

STL127705 is a potent small molecule inhibitor of Ku70/80 heterodimer protein with an IC50 of 3.5 μM. It disrupts Non-Homologous End-Joining (NHEJ) by preventing DNA binding and inhibiting DNA-PKCS activation. It exhibits anticancer activity by inducing apoptosis and inhibiting cell proliferation.