Asymmetric dimethylarginine is an endogenous inhibitor of nitric oxide synthase (NOS). It also functions as a marker of endothelial dysfunction in several pathological states.

Exatecan (DX-8951), is a water-soluble derivative of camptothecin. It acts as an inhibitor of DNA topoisomerase I with an IC50 value of 1.906 μM. It demonstrates potent antitumor effects and triggers apoptotic cell death after treatment in human pancreatic cancer cells.

Exatecan (DX-8951), is a water-soluble derivative of camptothecin. It acts as an inhibitor of DNA topoisomerase I with an IC50 value of 1.906 μM. It demonstrates potent antitumor effects and triggers apoptotic cell death after treatment in human pancreatic cancer cells.

Exatecan (DX-8951), is a water-soluble derivative of camptothecin. It acts as an inhibitor of DNA topoisomerase I with an IC50 value of 1.906 μM. It demonstrates potent antitumor effects and triggers apoptotic cell death after treatment in human pancreatic cancer cells.

Gypenoside L, is a saponin from Gynostemma pentaphyllum, increases SA-β-galactosidase activity, enhances senescence-associated cytokine production, inhibits proliferation and LPS-induced nitric oxide (NO) production, induces S-phase arrest, and activates p21, p27, p38, ERK MAPK, and NF-κB pathways to promote senescence.

Exatecan (DX-8951), is a water-soluble derivative of camptothecin. It acts as an inhibitor of DNA topoisomerase I with an IC50 value of 1.906 μM. It demonstrates potent antitumor effects and triggers apoptotic cell death after treatment in human pancreatic cancer cells.

Gypenoside L, is a saponin from Gynostemma pentaphyllum, increases SA-β-galactosidase activity, enhances senescence-associated cytokine production, inhibits proliferation and LPS-induced nitric oxide (NO) production, induces S-phase arrest, and activates p21, p27, p38, ERK MAPK, and NF-κB pathways to promote senescence.

Gypenoside L, is a saponin from Gynostemma pentaphyllum, increases SA-β-galactosidase activity, enhances senescence-associated cytokine production, inhibits proliferation and LPS-induced nitric oxide (NO) production, induces S-phase arrest, and activates p21, p27, p38, ERK MAPK, and NF-κB pathways to promote senescence.

DC_AC50 is an inhibitor of the copper-trafficking proteins Atox1 (kd ∼6.8 µM) and full-length CCS (kd ∼8.2 µM) that significantly suppressing cell proliferation in various human cancer cell lines.

Gypenoside L, is a saponin from Gynostemma pentaphyllum, increases SA-β-galactosidase activity, enhances senescence-associated cytokine production, inhibits proliferation and LPS-induced nitric oxide (NO) production, induces S-phase arrest, and activates p21, p27, p38, ERK MAPK, and NF-κB pathways to promote senescence.