PDK4-IN-1 hydrochloride is an anthraquinone-derived, orally active allosteric inhibitor of PDK4 with an IC50 of 84 nM, exhibiting anticancer activity by regulating cell proliferation, transformation, and apoptosis. It also exhibit antidiabeti and anti-allergic activity.

PDK4-IN-1 hydrochloride is an anthraquinone-derived, orally active allosteric inhibitor of PDK4 with an IC50 of 84 nM, exhibiting anticancer activity by regulating cell proliferation, transformation, and apoptosis. It also exhibit antidiabeti and anti-allergic activity.

PDK4-IN-1 hydrochloride is an anthraquinone-derived, orally active allosteric inhibitor of PDK4 with an IC50 of 84 nM, exhibiting anticancer activity by regulating cell proliferation, transformation, and apoptosis. It also exhibit antidiabeti and anti-allergic activity.

Nudifloramide (2PY, N-methyl-2-pyridone-5- carboxamide) is a pyridine derivative of nicotinamide that inhibits PARP-1 (poly (ADP-ribose) polymerase-1) activity in vitro, with an IC50 of 8 µM.

Nudifloramide (2PY, N-methyl-2-pyridone-5- carboxamide) is a pyridine derivative of nicotinamide that inhibits PARP-1 (poly (ADP-ribose) polymerase-1) activity in vitro, with an IC50 of 8 µM.

Nudifloramide (2PY, N-methyl-2-pyridone-5- carboxamide) is a pyridine derivative of nicotinamide that inhibits PARP-1 (poly (ADP-ribose) polymerase-1) activity in vitro, with an IC50 of 8 µM.

Acetyl phosphate(lithium potassium) is an endogenous metabolite, bypasses the LytS membrane potential sensor by phosphorylating LytR twice as fast, influencing lrgAB operon regulation in glucose-rich conditions without membrane potential disruption. Lithium potassium acetyl phosphate is studied for its electrochemical properties and role in phosphorus chemistry, with potential applications in lithium-ion battery technology and catalytic processes.

Nudifloramide (2PY, N-methyl-2-pyridone-5- carboxamide) is a pyridine derivative of nicotinamide that inhibits PARP-1 (poly (ADP-ribose) polymerase-1) activity in vitro, with an IC50 of 8 µM.

Acetyl phosphate(lithium potassium) is an endogenous metabolite, bypasses the LytS membrane potential sensor by phosphorylating LytR twice as fast, influencing lrgAB operon regulation in glucose-rich conditions without membrane potential disruption. Lithium potassium acetyl phosphate is studied for its electrochemical properties and role in phosphorus chemistry, with potential applications in lithium-ion battery technology and catalytic processes.

OICR-8268 is a potent, reversible and in-cell active DCAF1 ligand. It significantly binds to DCAF1 WDR domain with an Kd value of 38 nM. It serves as a promising starting point for developing chemical handles for DCAF1-based PROTACs targeting selective protein degradation as well as cancer therapeutics.