5,6-Dihydroxyindole is an indole derivative crucial for eumelanin biosynthesis, responsible for pigmentation in skin, hair, and eyes. With two hydroxyl groups, it acts as a strong antioxidant, scavenging reactive oxygen species (ROS) and reducing oxidative stress. It oxidizes through the Fenton reaction to form melanin, providing both pigmentation and protection against oxidative damage, especially in […]

PRDX1-IN-1 is a celastrol-ligustrazine hybrid and a potent inhibitor of peroxiredoxin 1 (PRDX1) with an IC50 of 0.164 μM. It induces ROS accumulation, inhibits cancer cell growth and metastasis, and exhibits strong antitumor efficacy, making it a promising candidate for lung cancer therapy.

5,6-Dihydroxyindole is an indole derivative crucial for eumelanin biosynthesis, responsible for pigmentation in skin, hair, and eyes. With two hydroxyl groups, it acts as a strong antioxidant, scavenging reactive oxygen species (ROS) and reducing oxidative stress. It oxidizes through the Fenton reaction to form melanin, providing both pigmentation and protection against oxidative damage, especially in […]

5,6-Dihydroxyindole is an indole derivative crucial for eumelanin biosynthesis, responsible for pigmentation in skin, hair, and eyes. With two hydroxyl groups, it acts as a strong antioxidant, scavenging reactive oxygen species (ROS) and reducing oxidative stress. It oxidizes through the Fenton reaction to form melanin, providing both pigmentation and protection against oxidative damage, especially in […]

5,6-Dihydroxyindole is an indole derivative crucial for eumelanin biosynthesis, responsible for pigmentation in skin, hair, and eyes. With two hydroxyl groups, it acts as a strong antioxidant, scavenging reactive oxygen species (ROS) and reducing oxidative stress. It oxidizes through the Fenton reaction to form melanin, providing both pigmentation and protection against oxidative damage, especially in […]

CCR6 antagonist 1 is a potent antagonist of CCR6 that inhibits the CCL20/CCR6 axis. It can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs).

CCR6 antagonist 1 is a potent antagonist of CCR6 that inhibits the CCL20/CCR6 axis. It can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs).

CCR6 antagonist 1 is a potent antagonist of CCR6 that inhibits the CCL20/CCR6 axis. It can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs).

CCR6 antagonist 1 is a potent antagonist of CCR6 that inhibits the CCL20/CCR6 axis. It can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs).

PT 3 is a benzamide-class, potent, and selective inhibitor of Histone Deacetylase 3 (HDAC3) with an IC50 of 245 nM. It crosses the blood-brain barrier and enhances learning and memory in novel object recognition models in mice.