RMC5127 is a first-in-class, orally bioavailable mutant-selective tri-complex inhibitor of the GTP-bound (ON) form of RASG12V. It non-covalently binds to cyclophilin A (CypA), forming a binary complex that engages RASG12V(ON) to form a high-affinity tri-complex, sterically inhibiting RAS binding. It inhibits the RAS pathway in KRASG12V-mutant cancer cells, reducing proliferation, inducing apoptosis, and showing strong […]

AUR1545 is a potent and selective degrader of KAT2A and KAT2B. It exhibits an anti-proliferative effect and significantly inhibits tumor growth in an NCI-H1048 xenograft model.

GSK4418959 is a non-covalent, reversible, selective and orally active inhibitor of WRN helicase. It inhibits ATPase and DNA unwinding functions in an ATP-competitive manner and can be a potential therapeutic agent that can be used for the study of microsatellite instability-high (MSI-H) cancer research.

Triamcinolone hexacetonide is a long-acting intra-articular corticosteroid used in rheumatology to treat rheumatoid arthritis and knee osteoarthritis. It shows dose-dependent protective effects against chemically induced cartilage damage and alters ectopic discharge when applied to a lingual nerve injury site.

AUR1545 is a potent and selective degrader of KAT2A and KAT2B. It exhibits an anti-proliferative effect and significantly inhibits tumor growth in an NCI-H1048 xenograft model.

Triamcinolone hexacetonide is a long-acting intra-articular corticosteroid used in rheumatology to treat rheumatoid arthritis and knee osteoarthritis. It shows dose-dependent protective effects against chemically induced cartilage damage and alters ectopic discharge when applied to a lingual nerve injury site.

Triamcinolone hexacetonide is a long-acting intra-articular corticosteroid used in rheumatology to treat rheumatoid arthritis and knee osteoarthritis. It shows dose-dependent protective effects against chemically induced cartilage damage and alters ectopic discharge when applied to a lingual nerve injury site.

Triamcinolone hexacetonide is a long-acting intra-articular corticosteroid used in rheumatology to treat rheumatoid arthritis and knee osteoarthritis. It shows dose-dependent protective effects against chemically induced cartilage damage and alters ectopic discharge when applied to a lingual nerve injury site.

Prednisolone tebutate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester primarily used for its anti-inflammatory and immunosuppressive effects. It significantly suppresses inflammatory responses in models of monosodium urate (MSU) crystal-induced inflammation.

Prednisolone tebutate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester primarily used for its anti-inflammatory and immunosuppressive effects. It significantly suppresses inflammatory responses in models of monosodium urate (MSU) crystal-induced inflammation.