ONPG is a colorimetric and spectrophotometric substrate for detection of β-galactosidase activity.

D-Glucose-13C6 is a stable isotope-labeled counterpart of D-glucose (HY-B0389). D-Glucose-13C6 can be used as a metabolic tracer to trace glucose-related synthetic catabolism or as synthesis ingredient, minimal media reagent, and internal standard.

Suc-Leu-Leu-Val-Tyr-AMC (Succinyl-leucyl-leucyl-valyl-tyrosyl-methylcoumarinamide) is a fluorescent substrate for the 20S proteasome, other chymotrypsin-like proteases, and calpains. Upon enzymatic cleavage, it releases the fluorescent AMC (7-amino-4-methylcoumarin) with an excitation maximum at 360 nm and an emission maximum at 460 nm.

Umifenovir is a potent, orally active broad-spectrum antiviral agent with activity against a number of enveloped and non-enveloped viruses. Umifenovir is used as an anti-influenza virus agent. Umifenovir could effectively inhibit the fusion of virus with host cells. Umifenovir is an efficient inhibitor of SARS-CoV-2 in vitro. Umifenovir shows anti-inflammatory activity.

Taurocholic acid (N-Choloyltaurine), a taurine-conjugated form of cholic acid, is a major bile acid elevated in liver disease. It promotes by activating hepatic stellate cells via TLR4 upregulation and exhibits anti-inflammatory effects in gingival fibroblasts, oral squamous carcinoma cells, and macrophages in vitro.

Uric acid sodium (Monosodium urate) is a scavenger of oxygen radical, is a very important antioxidant that help maintains the stability of blood pressure and antioxidant stress. It can remove reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite, inhibiting lipid peroxidation and may have protective effects as an antioxidant in human diseases such […]

Pilocarpine is a non-selective agonist of muscarinic acetylcholine receptor (mAChR), commonly used to treat xerostomia and glaucoma. It modulates the electrical properties of heart cells, likely by activating a potassium (K+) current mediated by M3 receptors.

Vonoprazan (TAK-438 free base), a proton pump inhibitor (PPI), is a potent and orally active potassium-competitive acid blocker (P-CAB), with antisecretory activity. It also inhibits H⁺, K⁺-ATPase activity in porcine gastric microsomes with an IC50 of 19 nM at pH 6.5. Vonoprazan is selected as a drug candidate for the treatment of gastroesophageal reflux disease […]

Glycerophospholipids, cephalins are amphipathic molecules and essential components of neural membranes that are required for neural membrane structure and the proper function of integral membrane proteins, receptors, transporters, and ion channels. They also participate in apoptosis, regulate transporter and membrane-bound enzyme activities, and also serve as storage depots for lipid mediators and are useful in […]

Ponatinib hydrochloride is a potent, orally available multi-targeted inhibitor of Pan BCR-ABL kinase. It potently inhibits ABL with an IC50 of 0.37 nM, also inhibits SRC , VEGFR2, FGFR1, PDGFRα, LYN with an IC50s of 5.4 nM, 1.5 nM, 2.2 nM, 1.1 nM, 0.24 nM respectively and exhibits significant potential in cancer reserach.