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Vitamin D4 (22-Dihydroergocalciferol) is a Vitamin D derived from fungi. The precursor of Vitamin D4 is 22,23-dihydroergosterol.

Licochalcone C could inhibit α-glucosidase, with IC50s of

Elacestrant (RAD1901) is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant also can inhibit growth of ER+ breast cancer cell lines in vitro and in vivo.

Guanosine 5′-diphosphate (GDP) disodium salt, a purine nucleoside diphosphate, is interconverted to guanosine by the action of exonucleotidase and phosphorylation of nucleoside to guanine. Guanosine 5′-diphosphate disodium salt activates adenosine 5′-triphosphate-sensitive K+ channel and is used to study the kinetics and characteristics of GTPases such as those associated with G-protein coupled receptors (GPCR). Guanosine 5′-diphosphate […]

Seocalcitol is a vitamin D analog, binds vitamin D receptor protein from human osteosarcoma MG-63 cells with Kd of 0.27 nM.

Sobetirome (GC-1, QRX431) is a potent and selective agonist of thyroid hormone receptor β (TRβ) , with an EC50 of 0.16 μM for TRβ-1. It is used in research for lowering LDL cholesterol and exploring potential treatments for heart disease, high cholesterol, and obesity.

Fagomine is a mild glycosidase inhibitor. The Ki of the iminosugar Fagomine is 4.8 μM, 39 μM, and 70 μM for Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast), respectively.

Uridine triphosphate (UTP) is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate activates membrane-bound P2Y2 receptors.

Deoxynivalenol (Vomitoxin) is an orally active trichothecene mycotoxin produced by Fusarium fungi, commonly contaminating cereal grains such as wheat, barley, and corn. It disrupts protein synthesis, impairs gut integrity, and triggers immune dysregulation, leading to vomiting, growth suppression, and inflammation in humans and animals. It also induces p38-mediated gene expression and apoptosis in leukocytes, promoting […]