Cefaclor is a well-absorbed orally active cephalosporin antibiotic. Cefaclor can specifically bind to specific for penicillin-binding protein 3 (PBP3). Cefaclor can be used for the research of depression and kinds of infections caused by bacteria, such as respiratory tract infections, bacterial bronchitis, pharyngitis and skin infections.

Ciglitazone is a potent and selective PPARγ agonist (EC50=3 μM). Ciglitazone inhibits proliferation and differentiation of th17 cells. Ciglitazone is a hypoglycemic agent orally active in the obese-hyperglycemic animal models. Ciglitazone induces apoptosis accompanied by activation of p38 MAPK and nuclear translocation of apoptosis inducing factor (AIF) in opossum kidney (OK) renal epithelial cells.

Tafluprost acid (AFP-172), the active metabolite of Tafluprost, is a selective agonist of the prostanoid FP receptor, with Ki and IC50 of 0.4 nM and 0.53 nM, respectively, for the human prostanoid FP receptor. It also exhibits 126-fold weaker binding affinity for the prostanoid EP3 receptor, with an IC50 of 67 nM, compared to the […]

β-Endorphin, human, a prominent endogenous peptide, existing in the hypophysis cerebri and hypothalamus, is an agonist of opioid receptor, with preferred affinity for μ-opioid receptor and δ-opioid receptor; β-Endorphin, human exhibits antinociception activity.

4-Diethylaminobenzaldehyde is a reversible aldehyde dehydrogenases (ALDHs) inhibitor, with a Ki of 4 nM for ALDH1. 4-Diethylaminobenzaldehyde displays potent anti-androgenic effect (IC50= 1.71μM).

CTAP is a potent, highly selective, and blood–brain barrier penetrant antagonist of μ opioid receptor with an IC50 of 3.5 nM. It displays over 1200-fold selectivity over δ opioid and somatostatin receptors. It exhibits anti-dyskinetic potential and can be used for the study of L-DOPA-induced dyskinesia (LID) and opiate overdose or addiction.

[Des-Arg9]-Bradykinin is a Bradykinin (B1) receptor agonist that displays selectivity for B1 over B2 receptors.

Fibronectin is a glycoprotein found in blood and cells, serving as a biomarker of tissue injury and playing a key role in promoting wound repair. It also binds to extracellular matrix proteins like collagen, fibrin, and heparan sulfate proteoglycans, with elevated plasma levels observed in conditions such as inflammation, trauma, exbiting a potential tool for […]

Diltiazem (Dilzen, CRD-401) is a benzothiazepine, an antagonist of Ca2+ channel inhibiting L-type Ca²⁺ currents via CaV1.2 channels in cardiac and vascular smooth muscle. It can be used in research of cardiac arrhythmia, hypertension, and angina pectoris.

Fibronectin is a glycoprotein found in blood and cells, serving as a biomarker of tissue injury and playing a key role in promoting wound repair. It also binds to extracellular matrix proteins like collagen, fibrin, and heparan sulfate proteoglycans, with elevated plasma levels observed in conditions such as inflammation, trauma, exbiting a potential tool for […]